Andrographis paniculata and Andrographolide - A Snapshot on Recent Advances in Nano Drug Delivery Systems against Cancer

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Cancer is one of the deadliest illnesses of the 21st century. Chemotherapy and radiation therapies both have considerable side effects. Antitumor antibiotics are one of them. Coughs, common colds, fevers, laryngitis, and infectious disorders have all been treated with Andrographis paniculata for centuries. Extracts of Andrographis effectively treat various ailments, as well as cancer. The most active molecule in Andrographis paniculata is andrographolide a, diterpene, and lactone. Andrographis paniculata and its derivatives have long been used to treat various ailments. Anti-inflammatory and cancerfighting characteristics have been observed in Andrographolide. Andrographolide, a diterpene lactone separated from Andrographis paniculata, has also been shown to have important criticalessential biological protective properties. It has also been suggested that it could be used to treat major human diseases like-rheumatoid like rheumatoid, colitis, and Parkinsons disease. This summary aims to highlight Andrographolide as a promising cancer treatment option. Several databases were searched for andrographolides cytotoxic/anti-cancer effects in pre-clinical and clinical research to serve this purpose. Several studies have shown that Andrographolide is helpful in cancer medication, as detailed in this review.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:21

Enthalten in:

Current drug delivery - 21(2024), 5 vom: 07., Seite 631-644

Sprache:

Englisch

Beteiligte Personen:

Deshmukh, Rohitas [VerfasserIn]
Jain, Aman Kumar [VerfasserIn]
Singh, Rajesh [VerfasserIn]
Paul, Swarnali Das [VerfasserIn]
Harwansh, Ranjit K [VerfasserIn]

Links:

Volltext

Themen:

410105JHGR
Andrographis paniculata
Andrographolide
Cancer
Diterpenes
Herbal bioactives.
Journal Article
Lactones
Nanocarriers
Nanoparticle Drug Delivery System
Nanoparticles
Plant Extracts
Review

Anmerkungen:

Date Completed 11.01.2024

Date Revised 11.01.2024

published: Print

Citation Status MEDLINE

doi:

10.2174/1567201820666230203115752

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM352507993