First case report of multivisceral transplant from a deceased cardiac death donor
Copyright © 2022 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved..
The current shortage of pediatric multivisceral donors accounts for the long time and mortality on the waiting list of pediatric patients. The use of donors after cardiac death, especially after the outbreak of normothermic regional perfusion, has increased in recent years for all solid organs except the intestine, mainly because of its higher susceptibility to ischemia-reperfusion injury. We present the first literature case of multivisceral donors after cardiac death transplantation in a 13-month-old recipient from a 2.5-month-old donor. Once exitus was certified, an extracorporeal membrane oxygenation circuit was established, cannulating the aorta and infrarenal vena cava, while the supra-aortic branches were clamped. The abdominal organs completely recovered from ischemia through normothermic regional perfusion (extracorporeal membrane oxygenation initially and beating heart later). After perfusion with the preservation solution, the multivisceral graft was uneventfully implanted. Two months later, the patient was discharged without any complications. This case demonstrates the possibility of reducing the time spent on the waiting list for these patients.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:23 |
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| Enthalten in: |
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 23(2023), 4 vom: 30. Apr., Seite 577-581 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Andres, Ane M [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 10.04.2023 Date Revised 17.04.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.ajt.2022.12.021 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
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| 245 | 1 | 0 | |a First case report of multivisceral transplant from a deceased cardiac death donor |
| 264 | 1 | |c 2023 | |
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| 500 | |a Date Revised 17.04.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2022 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. | ||
| 520 | |a The current shortage of pediatric multivisceral donors accounts for the long time and mortality on the waiting list of pediatric patients. The use of donors after cardiac death, especially after the outbreak of normothermic regional perfusion, has increased in recent years for all solid organs except the intestine, mainly because of its higher susceptibility to ischemia-reperfusion injury. We present the first literature case of multivisceral donors after cardiac death transplantation in a 13-month-old recipient from a 2.5-month-old donor. Once exitus was certified, an extracorporeal membrane oxygenation circuit was established, cannulating the aorta and infrarenal vena cava, while the supra-aortic branches were clamped. The abdominal organs completely recovered from ischemia through normothermic regional perfusion (extracorporeal membrane oxygenation initially and beating heart later). After perfusion with the preservation solution, the multivisceral graft was uneventfully implanted. Two months later, the patient was discharged without any complications. This case demonstrates the possibility of reducing the time spent on the waiting list for these patients | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a clinical research/practice | |
| 650 | 4 | |a donors and donation: donation after circulatory death (DCD) | |
| 650 | 4 | |a donors and donation: extended criteria | |
| 650 | 4 | |a intestinal disease: congenital | |
| 650 | 4 | |a intestine/multivisceral transplantation | |
| 650 | 4 | |a organ procurement and allocation | |
| 650 | 4 | |a translational research/science | |
| 650 | 4 | |a waitlist management | |
| 700 | 1 | |a Encinas, Jose Luis |e verfasserin |4 aut | |
| 700 | 1 | |a Sánchez-Galán, Alba |e verfasserin |4 aut | |
| 700 | 1 | |a Rodríguez, Javier Serradilla |e verfasserin |4 aut | |
| 700 | 1 | |a Estefania, Karla |e verfasserin |4 aut | |
| 700 | 1 | |a Sacristan, Rocio Gonzalez |e verfasserin |4 aut | |
| 700 | 1 | |a Alcolea, Alida |e verfasserin |4 aut | |
| 700 | 1 | |a Serrano, Pilar |e verfasserin |4 aut | |
| 700 | 1 | |a Estébanez, Belén |e verfasserin |4 aut | |
| 700 | 1 | |a Leon, Iñigo Velasco |e verfasserin |4 aut | |
| 700 | 1 | |a Burgos, Paula |e verfasserin |4 aut | |
| 700 | 1 | |a Rocafort, Alvaro Gonzalez |e verfasserin |4 aut | |
| 700 | 1 | |a Ramchandani, Bunty |e verfasserin |4 aut | |
| 700 | 1 | |a Calderón, Belén |e verfasserin |4 aut | |
| 700 | 1 | |a Verdú, Cristina |e verfasserin |4 aut | |
| 700 | 1 | |a Jimenez, Esperanza |e verfasserin |4 aut | |
| 700 | 1 | |a Talayero, Paloma |e verfasserin |4 aut | |
| 700 | 1 | |a Stringa, Pablo |e verfasserin |4 aut | |
| 700 | 1 | |a Navarro, Itziar de la Peña |e verfasserin |4 aut | |
| 700 | 1 | |a Ramos, Esther |e verfasserin |4 aut | |
| 700 | 1 | |a Oliveros, Francisco Hernandez |e verfasserin |4 aut | |
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