Preliminary safety and efficacy of laser stricturotomy for treatment of refractory biliary anastomotic strictures following liver transplantation
Copyright © 2022 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved..
Biliary anastomotic stricture (BAS) is a frequent complication of liver transplantation and is associated with reduced graft survival and patient morbidity. Existing treatments for BAS involve dilation of the stricture though placement of 1 or more catheters for 6 to 24 months yielding limited effectiveness in transplant patients. In this case series, we present preliminary safety and efficacy of a novel percutaneous laser stricturotomy treatment in a cohort of 5 posttransplant patients with BAS refractory to long-term large bore catheterization. In all patients, holmium or thulium laser was used to excise the stricture and promote biliary re-epithelization. There were no periprocedural complications. Technical success was 100% and at mean follow-up time of 22 months, there have been no recurrences. In conclusion, percutaneous laser stricturotomy demonstrates preliminary safety and efficacy in treatment of refractory BAS following liver transplantation.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:23 |
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| Enthalten in: |
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 23(2023), 4 vom: 24. Apr., Seite 573-576 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Trivedi, Premal [VerfasserIn] |
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| Links: |
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| Themen: |
Benign anastomotic stricture |
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| Anmerkungen: |
Date Completed 10.04.2023 Date Revised 17.04.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.ajt.2022.12.020 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM352062509 |
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| 520 | |a Copyright © 2022 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. | ||
| 520 | |a Biliary anastomotic stricture (BAS) is a frequent complication of liver transplantation and is associated with reduced graft survival and patient morbidity. Existing treatments for BAS involve dilation of the stricture though placement of 1 or more catheters for 6 to 24 months yielding limited effectiveness in transplant patients. In this case series, we present preliminary safety and efficacy of a novel percutaneous laser stricturotomy treatment in a cohort of 5 posttransplant patients with BAS refractory to long-term large bore catheterization. In all patients, holmium or thulium laser was used to excise the stricture and promote biliary re-epithelization. There were no periprocedural complications. Technical success was 100% and at mean follow-up time of 22 months, there have been no recurrences. In conclusion, percutaneous laser stricturotomy demonstrates preliminary safety and efficacy in treatment of refractory BAS following liver transplantation | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a benign anastomotic stricture | |
| 650 | 4 | |a clinical research/practice | |
| 650 | 4 | |a liver allograft function/dysfunction | |
| 650 | 4 | |a liver transplantation/hepatology | |
| 700 | 1 | |a Saben, Jessica L |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Lisa |e verfasserin |4 aut | |
| 700 | 1 | |a Malamon, John S |e verfasserin |4 aut | |
| 700 | 1 | |a Pomfret, Elizabeth |e verfasserin |4 aut | |
| 700 | 1 | |a Pshak, Thomas |e verfasserin |4 aut | |
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