Identifying the necessary capacities for the adaptation of a diabetes phenotyping algorithm in countries of differing economic development status
BACKGROUND: In 2019, the World Health Organization recognised diabetes as a clinically and pathophysiologically heterogeneous set of related diseases. Little is currently known about the diabetes phenotypes in the population of low- and middle-income countries (LMICs), yet identifying their different risks and aetiology has great potential to guide the development of more effective, tailored prevention and treatment.
OBJECTIVES: This study reviewed the scope of diabetes datasets, health information ecosystems, and human resource capacity in four countries to assess whether a diabetes phenotyping algorithm (developed under a companion study) could be successfully applied.
METHODS: The capacity assessment was undertaken with four countries: Trinidad, Malaysia, Kenya, and Rwanda. Diabetes programme staff completed a checklist of available diabetes data variables and then participated in semi-structured interviews about Health Information System (HIS) ecosystem conditions, diabetes programme context, and human resource needs. Descriptive analysis was undertaken.
RESULTS: Only Malaysia collected the full set of the required diabetes data for the diabetes algorithm, although all countries did collect the required diabetes complication data. An HIS ecosystem existed in all settings, with variations in data hosting and sharing. All countries had access to HIS or ICT support, and epidemiologists or biostatisticians to support dataset preparation and algorithm application.
CONCLUSIONS: Malaysia was found to be most ready to apply the phenotyping algorithm. A fundamental impediment in the other settings was the absence of several core diabetes data variables. Additionally, if countries digitise diabetes data collection and centralise diabetes data hosting, this will simplify dataset preparation for algorithm application. These issues reflect common LMIC health systems' weaknesses in relation to diabetes care, and specifically highlight the importance of investment in improving diabetes data, which can guide population-tailored prevention and management approaches.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:16 |
|---|---|
| Enthalten in: |
Global health action - 16(2023), 1 vom: 31. Dez., Seite 2157542 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Jackson-Morris, Angela [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Diabetes |
|---|
| Anmerkungen: |
Date Completed 26.01.2023 Date Revised 08.02.2023 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.1080/16549716.2022.2157542 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM352031549 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM352031549 | ||
| 003 | DE-627 | ||
| 005 | 20231226052808.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1080/16549716.2022.2157542 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1173.xml |
| 035 | |a (DE-627)NLM352031549 | ||
| 035 | |a (NLM)36692486 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Jackson-Morris, Angela |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Identifying the necessary capacities for the adaptation of a diabetes phenotyping algorithm in countries of differing economic development status |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 26.01.2023 | ||
| 500 | |a Date Revised 08.02.2023 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: In 2019, the World Health Organization recognised diabetes as a clinically and pathophysiologically heterogeneous set of related diseases. Little is currently known about the diabetes phenotypes in the population of low- and middle-income countries (LMICs), yet identifying their different risks and aetiology has great potential to guide the development of more effective, tailored prevention and treatment | ||
| 520 | |a OBJECTIVES: This study reviewed the scope of diabetes datasets, health information ecosystems, and human resource capacity in four countries to assess whether a diabetes phenotyping algorithm (developed under a companion study) could be successfully applied | ||
| 520 | |a METHODS: The capacity assessment was undertaken with four countries: Trinidad, Malaysia, Kenya, and Rwanda. Diabetes programme staff completed a checklist of available diabetes data variables and then participated in semi-structured interviews about Health Information System (HIS) ecosystem conditions, diabetes programme context, and human resource needs. Descriptive analysis was undertaken | ||
| 520 | |a RESULTS: Only Malaysia collected the full set of the required diabetes data for the diabetes algorithm, although all countries did collect the required diabetes complication data. An HIS ecosystem existed in all settings, with variations in data hosting and sharing. All countries had access to HIS or ICT support, and epidemiologists or biostatisticians to support dataset preparation and algorithm application | ||
| 520 | |a CONCLUSIONS: Malaysia was found to be most ready to apply the phenotyping algorithm. A fundamental impediment in the other settings was the absence of several core diabetes data variables. Additionally, if countries digitise diabetes data collection and centralise diabetes data hosting, this will simplify dataset preparation for algorithm application. These issues reflect common LMIC health systems' weaknesses in relation to diabetes care, and specifically highlight the importance of investment in improving diabetes data, which can guide population-tailored prevention and management approaches | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Diabetes | |
| 650 | 4 | |a LMICs | |
| 650 | 4 | |a health information system | |
| 650 | 4 | |a non-communicable diseases | |
| 650 | 4 | |a phenotype | |
| 700 | 1 | |a Sembajwe, Rita |e verfasserin |4 aut | |
| 700 | 1 | |a Mustapha, Feisul Idzwan |e verfasserin |4 aut | |
| 700 | 1 | |a Chandran, Arunah |e verfasserin |4 aut | |
| 700 | 1 | |a Niyonsenga, Simon Pierre |e verfasserin |4 aut | |
| 700 | 1 | |a Gishoma, Crispin |e verfasserin |4 aut | |
| 700 | 1 | |a Onyango, Elizabeth |e verfasserin |4 aut | |
| 700 | 1 | |a Muriuki, Zachariah |e verfasserin |4 aut | |
| 700 | 1 | |a Dharamraj, Kavita |e verfasserin |4 aut | |
| 700 | 1 | |a Ellermeier, Nathan |e verfasserin |4 aut | |
| 700 | 1 | |a Nugent, Rachel |e verfasserin |4 aut | |
| 700 | 1 | |a Kazlauskaite, Rasa |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Global health action |d 2008 |g 16(2023), 1 vom: 31. Dez., Seite 2157542 |w (DE-627)NLM193914522 |x 1654-9880 |7 nnns |
| 773 | 1 | 8 | |g volume:16 |g year:2023 |g number:1 |g day:31 |g month:12 |g pages:2157542 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1080/16549716.2022.2157542 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 16 |j 2023 |e 1 |b 31 |c 12 |h 2157542 | ||