Real world reduction in red cell transfusion with restrictive transfusion threshold in haematology inpatients
© 2023 British Blood Transfusion Society..
OBJECTIVES: The aim of this study was to assess the reduction in red cell transfusions following a change in the red cell transfusion threshold for haematology inpatients from 80 to 70 g/L.
BACKGROUND: Haematology patients are among the high users of red blood cells. We reduced the threshold for transfusion of haematology inpatients to 70 g/L. This was based on evidence provided by randomised controlled trial published in 2020 that showed restrictive transfusion is non-inferior to liberal transfusion.
METHOD: We assessed red cell transfusions for haematology inpatients at Oxford University Hospitals NHS Foundation Trust for 9 months before and 9 months after a change in red cell transfusion threshold from 80 to 70 g/L.
RESULTS: After the change in threshold to 70 g/L or less from 80 g/L, the median number of red cell transfusions per month reduced to 88 from 111. This was a 23% reduction in the total number of red cells administered per month.
CONCLUSION: These results show the real-world reductions in transfusion that can be made by putting local transfusion guidelines in line with the international recommendations. This is of particular importance at a time of national blood shortage.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:33 |
|---|---|
| Enthalten in: |
Transfusion medicine (Oxford, England) - 33(2023), 3 vom: 01. Juni, Seite 254-256 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Pervaiz, Omer [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 15.06.2023 Date Revised 15.06.2023 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1111/tme.12952 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM351912118 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM351912118 | ||
| 003 | DE-627 | ||
| 005 | 20231226052526.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1111/tme.12952 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1172.xml |
| 035 | |a (DE-627)NLM351912118 | ||
| 035 | |a (NLM)36680494 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Pervaiz, Omer |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Real world reduction in red cell transfusion with restrictive transfusion threshold in haematology inpatients |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 15.06.2023 | ||
| 500 | |a Date Revised 15.06.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2023 British Blood Transfusion Society. | ||
| 520 | |a OBJECTIVES: The aim of this study was to assess the reduction in red cell transfusions following a change in the red cell transfusion threshold for haematology inpatients from 80 to 70 g/L | ||
| 520 | |a BACKGROUND: Haematology patients are among the high users of red blood cells. We reduced the threshold for transfusion of haematology inpatients to 70 g/L. This was based on evidence provided by randomised controlled trial published in 2020 that showed restrictive transfusion is non-inferior to liberal transfusion | ||
| 520 | |a METHOD: We assessed red cell transfusions for haematology inpatients at Oxford University Hospitals NHS Foundation Trust for 9 months before and 9 months after a change in red cell transfusion threshold from 80 to 70 g/L | ||
| 520 | |a RESULTS: After the change in threshold to 70 g/L or less from 80 g/L, the median number of red cell transfusions per month reduced to 88 from 111. This was a 23% reduction in the total number of red cells administered per month | ||
| 520 | |a CONCLUSION: These results show the real-world reductions in transfusion that can be made by putting local transfusion guidelines in line with the international recommendations. This is of particular importance at a time of national blood shortage | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a HSCT | |
| 650 | 4 | |a haematology | |
| 650 | 4 | |a restrictive | |
| 650 | 4 | |a transfusion | |
| 700 | 1 | |a Dhanapal, Jay |e verfasserin |4 aut | |
| 700 | 1 | |a Pillai, Lakshmi |e verfasserin |4 aut | |
| 700 | 1 | |a Pavord, Sue |e verfasserin |4 aut | |
| 700 | 1 | |a Leary, Heather |e verfasserin |4 aut | |
| 700 | 1 | |a Eyre, Toby |e verfasserin |4 aut | |
| 700 | 1 | |a Peniket, Andrew |e verfasserin |4 aut | |
| 700 | 1 | |a Staves, Julie |e verfasserin |4 aut | |
| 700 | 1 | |a Polzella, Paolo |e verfasserin |4 aut | |
| 700 | 1 | |a Desborough, Michael J R |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Transfusion medicine (Oxford, England) |d 1992 |g 33(2023), 3 vom: 01. Juni, Seite 254-256 |w (DE-627)NLM012655937 |x 1365-3148 |7 nnns |
| 773 | 1 | 8 | |g volume:33 |g year:2023 |g number:3 |g day:01 |g month:06 |g pages:254-256 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1111/tme.12952 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 33 |j 2023 |e 3 |b 01 |c 06 |h 254-256 | ||