Acanthamoeba meningoencephalitis causing secondary hemophagocytic lymphohistiocytosis in an immunocompetent patient : A first case report
Acanthamoeba is a rare cause of granulomatous amoebic encephalitis (GAE) associated with high mortality. There have been few case reports of Acanthamoeba meningoencephalitis worldwide. Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory condition caused by abnormally active macrophages and cytotoxic T lymphocytes; its secondary form is due to infections or malignancies. However, HLH is rather an unknown complication of GAE. We describe an unusual and previously unreported case of Acanthamoeba meningoencephalitis in a young immunocompetent female culminating in secondary HLH.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:53 |
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| Enthalten in: |
The journal of the Royal College of Physicians of Edinburgh - 53(2023), 1 vom: 21. März, Seite 23-26 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Chowdhury, Mohit [VerfasserIn] |
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| Links: |
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| Themen: |
Acanthamoeba meningoencephalitis |
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| Anmerkungen: |
Date Completed 18.04.2023 Date Revised 15.08.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1177/14782715221149709 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM351910727 |
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| 245 | 1 | 0 | |a Acanthamoeba meningoencephalitis causing secondary hemophagocytic lymphohistiocytosis in an immunocompetent patient |b A first case report |
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| 520 | |a Acanthamoeba is a rare cause of granulomatous amoebic encephalitis (GAE) associated with high mortality. There have been few case reports of Acanthamoeba meningoencephalitis worldwide. Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory condition caused by abnormally active macrophages and cytotoxic T lymphocytes; its secondary form is due to infections or malignancies. However, HLH is rather an unknown complication of GAE. We describe an unusual and previously unreported case of Acanthamoeba meningoencephalitis in a young immunocompetent female culminating in secondary HLH | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Acanthamoeba meningoencephalitis | |
| 650 | 4 | |a hemophagocytic lympho-histiocytosis | |
| 650 | 4 | |a immunocompetent | |
| 700 | 1 | |a Prakash, Prithivi Raaj |e verfasserin |4 aut | |
| 700 | 1 | |a Singh, Amandeep |e verfasserin |4 aut | |
| 700 | 1 | |a Jorwal, Pankaj |e verfasserin |4 aut | |
| 700 | 1 | |a Das, Sumanta |e verfasserin |4 aut | |
| 700 | 1 | |a Soneja, Manish |e verfasserin |4 aut | |
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