Contemporary therapy in atopic dermatitis; selected issues

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Atopic dermatitis is a chronic and recurrent inflammatory dermatosis, usually beginning in early childhood. The main symptoms are intense itching and dryness of the skin, erythematous inflammatory skin lesions with eczema morphology, and in the chronic phase lichenification and epidermal peeling. The characteristic localization is elbow and knee bends, face and neck. It is believed that 60% of AD cases begin before the age of 1 year, and 90% of all cases have an onset before the age of 5 years. The pathogenesis of the disease is complex. Genetic, immunological, environmental and psychological factors are involved. An important factor affecting the disease is a defect in the epidermal barrier, which results from abnormal expression of proteins such as filaggrin, abnormal composition of stratum corneum lipids, and skin colonization by Staphylococcus aureus. The basic treatment of the disease is to alleviate its symptoms, restore the epidermal barrier and prevent its recurrence. The aim of this paper is to present the possibilities of prophylaxis and treatment of patients with AD depending on the intensity of disease symptoms. The increasing incidence of AD is a problem not only in dermatology, but also in pediatrics and family medicine. It should be kept in mind that effective treatment of AD requires experience, strategy and good doctor-patient cooperation.

Medienart:

Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:50

Enthalten in:

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego - 50(2022), 300 vom: 22. Dez., Seite 395-397

Sprache:

Polnisch

Weiterer Titel:

Współczesna terapia w atopowym zapaleniu skóry; wybrane zagadnienia

Beteiligte Personen:

Ziębakowska, Marta [VerfasserIn]

Themen:

Atopic dermatitis
English Abstract
Epidermal barrier
Erythematous eczema
Inflammatory dermatosis
Journal Article
Lichenification
Review

Anmerkungen:

Date Completed 19.01.2023

Date Revised 19.01.2023

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM351565787