The Long Telling Story of "Endothelial Progenitor Cells" : Where Are We at Now?

Endothelial progenitor cells (EPCs): The name embodies years of research and clinical expectations, but where are we now? Do these cells really represent the El Dorado of regenerative medicine? Here, past and recent literature about this eclectic, still unknown and therefore fascinating cell population will be discussed. This review will take the reader through a temporal journey that, from the first discovery, will pass through years of research devoted to attempts at their definition and understanding their biology in health and disease, ending with the most recent evidence about their pathobiological role in cardiovascular disease and their recent applications in regenerative medicine.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:12

Enthalten in:

Cells - 12(2022), 1 vom: 28. Dez.

Sprache:

Englisch

Beteiligte Personen:

Vinci, Maria Cristina [VerfasserIn]
Carulli, Ermes [VerfasserIn]
Rurali, Erica [VerfasserIn]
Rinaldi, Raffaella [VerfasserIn]
Damiano, Giulia [VerfasserIn]
Raucci, Angela [VerfasserIn]
Pompilio, Giulio [VerfasserIn]
Genovese, Stefano [VerfasserIn]

Links:

Volltext

Themen:

Angiogenesis
CD34+ hematopoietic stem progenitor cells
Cardiovascular disease
Endothelial progenitor cells
Journal Article
Regenerative medicine
Research Support, Non-U.S. Gov't
Review

Anmerkungen:

Date Completed 10.01.2023

Date Revised 05.02.2023

published: Electronic

Citation Status MEDLINE

doi:

10.3390/cells12010112

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM351229981