Case Report : Isosulfan Blue-Related Anaphylaxis
Published by Oxford University Press on behalf of the Association of Military Surgeons of the United States 2023. This work is written by (a) US Government employee(s) and is in the public domain in the US..
Anaphylaxis is an acute multisystem syndrome typically resulting from the sudden release of mast cell and basophil-derived mediators into the circulatory system. Isosulfan blue dye is a rare, but known, mediator of anaphylaxis with an incidence between 0.16% and 2% of cases. We report two cases of anaphylaxis attributed to the use of isosulfan blue dye in the intraoperative setting. Both of the patients we report had grade 3 anaphylactic reactions requiring vasopressors to correct significant hypotension. Both patients required overnight monitoring in the intensive care unit with the second patient also requiring continued vasopressor support.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:188 |
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| Enthalten in: |
Military medicine - 188(2023), 11-12 vom: 03. Nov., Seite e3699-e3702 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Adams, Jacob [VerfasserIn] |
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| Links: |
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| Themen: |
39N9K8S2A4 |
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| Anmerkungen: |
Date Completed 09.11.2023 Date Revised 17.11.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.1093/milmed/usac419 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM351220836 |
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| 520 | |a Anaphylaxis is an acute multisystem syndrome typically resulting from the sudden release of mast cell and basophil-derived mediators into the circulatory system. Isosulfan blue dye is a rare, but known, mediator of anaphylaxis with an incidence between 0.16% and 2% of cases. We report two cases of anaphylaxis attributed to the use of isosulfan blue dye in the intraoperative setting. Both of the patients we report had grade 3 anaphylactic reactions requiring vasopressors to correct significant hypotension. Both patients required overnight monitoring in the intensive care unit with the second patient also requiring continued vasopressor support | ||
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