Clinical usefulness of end-tidal CO2 measured using a portable capnometer in patients with respiratory disease
© 2023 The Authors. The Clinical Respiratory Journal published by John Wiley & Sons Ltd..
INTRODUCTION: This study aimed to evaluate the correlation and agreement between end-tidal CO2 (EtCO2 ) measured with the novel portable capnometer (CapnoEye®) and partial pressure of arterial carbon dioxide (PaCO2 ) levels in patients with respiratory diseases and to compare the efficacy of EtCO2 and PvCO2 in predicting PaCO2 levels.
METHODS: We analyzed the correlation and the agreement between EtCO2 and PaCO2 and between PvCO2 and PaCO2 using Pearson's moment correlation coefficient in patients with type 1 and type 2 respiratory failure and both groups overall.
RESULTS: A total of 100 samples were included that comprised 67 men (67%). The mean age of the subjects was 77 ± 13 years. Chronic obstructive pulmonary disease (COPD) (43%) was the most common disease. There was a high correlation between EtCO2 and PaCO2 (r = 0.88; p < 0.0001). Sixty-six PvCO2 samples were obtained, and there was a high correlation between PvCO2 and PaCO2 (r = 0.81; p < 0.0001). Regarding type 2 respiratory failure, there was a high correlation between EtCO2 and PaCO2 (r = 0.81). The Bland-Altman analysis between PaCO2 and EtCO2 revealed a bias of 5.7 mmHg, with limits of agreement ranging from -5.1 mmHg to 16.5 mmHg. In contrast, the analysis between PaCO2 and PvCO2 revealed a bias of -6.8 mmHg, and the limits of agreement ranged from -22.13 mmHg to 8.53 mmHg.
CONCLUSION: EtCO2 measured by CapnoEye® was significantly correlated to PaCO2 levels in patients with respiratory diseases. Moreover, CapnoEye® may be more useful for predicting hypercapnia conditions in which respiratory diseases are compared with measure PvCO2.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:17 |
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| Enthalten in: |
The clinical respiratory journal - 17(2023), 2 vom: 06. Feb., Seite 96-104 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Suzuki, Manabu [VerfasserIn] |
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| Links: |
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| Themen: |
142M471B3J |
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| Anmerkungen: |
Date Completed 03.02.2023 Date Revised 07.02.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1111/crj.13577 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM351211446 |
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| 245 | 1 | 0 | |a Clinical usefulness of end-tidal CO2 measured using a portable capnometer in patients with respiratory disease |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2023 The Authors. The Clinical Respiratory Journal published by John Wiley & Sons Ltd. | ||
| 520 | |a INTRODUCTION: This study aimed to evaluate the correlation and agreement between end-tidal CO2 (EtCO2 ) measured with the novel portable capnometer (CapnoEye®) and partial pressure of arterial carbon dioxide (PaCO2 ) levels in patients with respiratory diseases and to compare the efficacy of EtCO2 and PvCO2 in predicting PaCO2 levels | ||
| 520 | |a METHODS: We analyzed the correlation and the agreement between EtCO2 and PaCO2 and between PvCO2 and PaCO2 using Pearson's moment correlation coefficient in patients with type 1 and type 2 respiratory failure and both groups overall | ||
| 520 | |a RESULTS: A total of 100 samples were included that comprised 67 men (67%). The mean age of the subjects was 77 ± 13 years. Chronic obstructive pulmonary disease (COPD) (43%) was the most common disease. There was a high correlation between EtCO2 and PaCO2 (r = 0.88; p < 0.0001). Sixty-six PvCO2 samples were obtained, and there was a high correlation between PvCO2 and PaCO2 (r = 0.81; p < 0.0001). Regarding type 2 respiratory failure, there was a high correlation between EtCO2 and PaCO2 (r = 0.81). The Bland-Altman analysis between PaCO2 and EtCO2 revealed a bias of 5.7 mmHg, with limits of agreement ranging from -5.1 mmHg to 16.5 mmHg. In contrast, the analysis between PaCO2 and PvCO2 revealed a bias of -6.8 mmHg, and the limits of agreement ranged from -22.13 mmHg to 8.53 mmHg | ||
| 520 | |a CONCLUSION: EtCO2 measured by CapnoEye® was significantly correlated to PaCO2 levels in patients with respiratory diseases. Moreover, CapnoEye® may be more useful for predicting hypercapnia conditions in which respiratory diseases are compared with measure PvCO2 | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a EtCO2 | |
| 650 | 4 | |a PaCO2 | |
| 650 | 4 | |a PvCO2 | |
| 650 | 4 | |a capnometer | |
| 650 | 4 | |a respiratory care | |
| 650 | 4 | |a respiratory medicine | |
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| 650 | 7 | |a 142M471B3J |2 NLM | |
| 700 | 1 | |a Fujimoto, Shota |e verfasserin |4 aut | |
| 700 | 1 | |a Sakamoto, Keita |e verfasserin |4 aut | |
| 700 | 1 | |a Tamura, Kentaro |e verfasserin |4 aut | |
| 700 | 1 | |a Ishii, Satoru |e verfasserin |4 aut | |
| 700 | 1 | |a Iikura, Motoyasu |e verfasserin |4 aut | |
| 700 | 1 | |a Izumi, Shinyu |e verfasserin |4 aut | |
| 700 | 1 | |a Takeda, Yuichiro |e verfasserin |4 aut | |
| 700 | 1 | |a Hojo, Masayuki |e verfasserin |4 aut | |
| 700 | 1 | |a Sugiyama, Haruhito |e verfasserin |4 aut | |
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