Acceptance Rate and Reasons for Rejection of Long Acting Injectable Antiretrovirals

© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature..

In January 2021, cabotegravir/rilpivirine, the first extended-release injectable regimen for the treatment of Human Immunodeficiency Virus (HIV) was approved. Long-acting injections have the potential to improve adherence and viral suppression. We analyzed the acceptance rate of, and reasons for declining to switch to, the new regimen. During routine appointments, 102 people living with HIV (PLWH) were presented with information on the new medication and asked if they would like to switch from their current regimen. If they declined to switch, they were asked why. Sixty-nine percent of respondents declined to switch, with frequency of injections as the primary reason. Patients indicated they would be willing to switch if the interval between injections was longer. Forty percent of the patients accepting the injectable anti-retrovirals (ARVs) were not on any other medications. Barriers to switching to long-acting injectable ARVs include the need for more frequent provider visits, aversion to needles, and a perceived lack of evidence supporting the new medication.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:27

Enthalten in:

AIDS and behavior - 27(2023), 7 vom: 28. Juli, Seite 2370-2375

Sprache:

Englisch

Beteiligte Personen:

Feihel, Dennis [VerfasserIn]
Spier, Daniel [VerfasserIn]
Stevens, Ty [VerfasserIn]
Stefanov, Dimitre G [VerfasserIn]
Ahmadi, Ladan [VerfasserIn]

Links:

Volltext

Themen:

Adherence
Anti-HIV Agents
Anti-Retroviral Agents
Cabotegravir
FI96A8X663
Injectable
Journal Article
Rilpivirine

Anmerkungen:

Date Completed 29.05.2023

Date Revised 29.05.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1007/s10461-022-03964-3

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM35088062X