Executive summary of the consensus document of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) on the diagnosis and antimicrobial treatment of infections due to carbapenem-resistant Gram-negative bacteria

Copyright © 2022 Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. Published by Elsevier España, S.L.U. All rights reserved..

Infections caused by multidrug resistant Gram-negative bacteria are becoming a worldwide problem due to their increasing incidence and associated high mortality. Carbapenem-resistant bacteria such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii are the most important in clinical practice. The objective of these guidelines is to update the recommendations for the diagnosis and treatment of infections caused by these multidrug resistant bacteria. Although 'old' antibiotics such as aminoglycosides, colistin, or tigecycline are frequently used for therapy of these bacteria, the 'new' beta-lactams such as ceftazidime-avibactam, ceftolozane-tazobactam, meropenem-vaborbactam, imipenem-cilastatin-relebactam or cefiderocol are progressively becoming the first-line therapy for most of these microorganisms. The Spanish Society of Infectious Diseases and Clinical Microbiology (Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica) designated a panel of experts in the field to provide evidence-based recommendations in response to common clinical questions. This document is primarily focused on microbiological diagnosis, clinical management, and targeted antimicrobial therapy of these infections, with special attention to defining the role of the new antimicrobials in the treatment of these bacteria.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:41

Enthalten in:

Enfermedades infecciosas y microbiologia clinica (English ed.) - 41(2023), 6 vom: 19. Juni, Seite 360-370

Sprache:

Englisch

Beteiligte Personen:

Pintado, Vicente [VerfasserIn]
Ruiz-Garbajosa, Patricia [VerfasserIn]
Aguilera-Alonso, David [VerfasserIn]
Baquero-Artigao, Fernando [VerfasserIn]
Bou, Germán [VerfasserIn]
Cantón, Rafael [VerfasserIn]
Grau, Santiago [VerfasserIn]
Gutiérrez-Gutiérrez, Belén [VerfasserIn]
Larrosa, Nieves [VerfasserIn]
Machuca, Isabel [VerfasserIn]
Martínez Martínez, Luis [VerfasserIn]
Montero, María Milagro [VerfasserIn]
Morte-Romea, Elena [VerfasserIn]
Oliver, Antonio [VerfasserIn]
Paño-Pardo, José Ramón [VerfasserIn]
Sorlí, Luisa [VerfasserIn]

Links:

Volltext

Themen:

Acinetobacter baumannii
Anti-Bacterial Agents
Bacterias gramnegativas
Carbapenem-resistant
Carbapenemase-producing Enterobacterales
Carbapenems
Enterobacterales productores de carbapenemasa
Gram-negative bacteria
Journal Article
Multidrug resistant
Multirresistentes
Practice Guideline
Pseudomonas aeruginosa
Resistentes a carbapenémicos
Stenotrophomonas maltophilia
Targeted antimicrobial therapy
Terapia antibiótica dirigida

Anmerkungen:

Date Completed 05.06.2023

Date Revised 28.07.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.eimce.2022.06.014

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM350341982