A review of COVID-19 therapeutics in pregnancy and lactation

© The Author(s) 2022..

Pregnant people have an elevated risk of severe COVID-19-related complications compared to their non-pregnant counterparts, underscoring the need for safe and effective therapies. In this review, we summarize published data on COVID-19 therapeutics in pregnancy and lactation to help inform clinical decision-making about their use in this population. Although no serious safety signals have been raised for many agents, data clearly have serious limitations and there are many important knowledge gaps about the safety and efficacy of key therapeutics used for COVID-19. Moving forward, diligent follow-up and documentation of outcomes in pregnant people treated with these agents will be essential to advance our understanding. Greater regulatory push and incentives are needed to ensure studies to obtain pregnancy data are expedited.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:15

Enthalten in:

Obstetric medicine - 15(2022), 4 vom: 09. Dez., Seite 225-232

Sprache:

Englisch

Beteiligte Personen:

Jorgensen, Sarah Cj [VerfasserIn]
Tabbara, Najla [VerfasserIn]
Burry, Lisa [VerfasserIn]

Links:

Volltext

Themen:

Bamlanivimab
Baricitinib
COVID-19
Casirivimab
Corticosteroids
Etesevimab
Imdevimab, monoclonal antibodies
Journal Article
Lactation
Remdesivir
Review
Severe acute respiratory syndrome-coronavirus-2
Tocilizumab

Anmerkungen:

Date Revised 22.12.2022

published: Print-Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.1177/1753495X211056211

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM350267995