Nutritional implications in the mechanistic link between the intestinal microbiome, renin-angiotensin system, and the development of obesity and metabolic syndrome
Copyright © 2022 Elsevier Inc. All rights reserved..
Obesity and metabolic disorders represent a significant global health problem and the gut microbiota plays an important role in modulating systemic homeostasis. Recent evidence shows that microbiota and its signaling pathways may affect the whole metabolism and the Renin-Angiotensin System (RAS), which in turn seems to modify microbiota. The present review aimed to investigate nutritional implications in the mechanistic link between the intestinal microbiome, renin-angiotensin system, and the development of obesity and metabolic syndrome components. A description of metabolic changes was obtained based on relevant scientific literature. The molecular and physiological mechanisms that impact the human microbiome were addressed, including the gut microbiota associated with obesity, diabetes, and hepatic steatosis. The RAS interaction signaling and modulation were analyzed. Strategies including the use of prebiotics, symbiotics, probiotics, and biotechnology may affect the gut microbiota and its impact on human health.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:113 |
|---|---|
| Enthalten in: |
The Journal of nutritional biochemistry - 113(2023) vom: 20. März, Seite 109252 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Guimarães, Victor Hugo Dantas [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Gut microbiota |
|---|
| Anmerkungen: |
Date Completed 23.02.2023 Date Revised 08.03.2023 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.jnutbio.2022.109252 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM350214565 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM350214565 | ||
| 003 | DE-627 | ||
| 005 | 20231226044508.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.jnutbio.2022.109252 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1167.xml |
| 035 | |a (DE-627)NLM350214565 | ||
| 035 | |a (NLM)36509338 | ||
| 035 | |a (PII)S0955-2863(22)00320-5 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Guimarães, Victor Hugo Dantas |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Nutritional implications in the mechanistic link between the intestinal microbiome, renin-angiotensin system, and the development of obesity and metabolic syndrome |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 23.02.2023 | ||
| 500 | |a Date Revised 08.03.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2022 Elsevier Inc. All rights reserved. | ||
| 520 | |a Obesity and metabolic disorders represent a significant global health problem and the gut microbiota plays an important role in modulating systemic homeostasis. Recent evidence shows that microbiota and its signaling pathways may affect the whole metabolism and the Renin-Angiotensin System (RAS), which in turn seems to modify microbiota. The present review aimed to investigate nutritional implications in the mechanistic link between the intestinal microbiome, renin-angiotensin system, and the development of obesity and metabolic syndrome components. A description of metabolic changes was obtained based on relevant scientific literature. The molecular and physiological mechanisms that impact the human microbiome were addressed, including the gut microbiota associated with obesity, diabetes, and hepatic steatosis. The RAS interaction signaling and modulation were analyzed. Strategies including the use of prebiotics, symbiotics, probiotics, and biotechnology may affect the gut microbiota and its impact on human health | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Gut microbiota | |
| 650 | 4 | |a Metabolic syndrome | |
| 650 | 4 | |a Microbial Therapy | |
| 650 | 4 | |a Nutrition | |
| 650 | 4 | |a Obesity | |
| 650 | 4 | |a Renin-Angiotensin System | |
| 650 | 7 | |a Prebiotics |2 NLM | |
| 700 | 1 | |a Marinho, Barbhara Mota |e verfasserin |4 aut | |
| 700 | 1 | |a Motta-Santos, Daisy |e verfasserin |4 aut | |
| 700 | 1 | |a Mendes, Gabriela da Rocha Lemos |e verfasserin |4 aut | |
| 700 | 1 | |a Santos, Sérgio Henrique Sousa |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t The Journal of nutritional biochemistry |d 1990 |g 113(2023) vom: 20. März, Seite 109252 |w (DE-627)NLM089754956 |x 1873-4847 |7 nnns |
| 773 | 1 | 8 | |g volume:113 |g year:2023 |g day:20 |g month:03 |g pages:109252 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.jnutbio.2022.109252 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 113 |j 2023 |b 20 |c 03 |h 109252 | ||