Nanomaterials to combat SARS-CoV-2 : Strategies to prevent, diagnose and treat COVID-19

Copyright © 2022 Valenzuela-Fernández, Cabrera-Rodriguez, Ciuffreda, Perez-Yanes, Estevez-Herrera, González-Montelongo, Alcoba-Florez, Trujillo-González, García-Martínez de Artola, Gil-Campesino, Díez-Gil, Lorenzo-Salazar, Flores and Garcia-Luis..

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the associated coronavirus disease 2019 (COVID-19), which severely affect the respiratory system and several organs and tissues, and may lead to death, have shown how science can respond when challenged by a global emergency, offering as a response a myriad of rapid technological developments. Development of vaccines at lightning speed is one of them. SARS-CoV-2 outbreaks have stressed healthcare systems, questioning patients care by using standard non-adapted therapies and diagnostic tools. In this scenario, nanotechnology has offered new tools, techniques and opportunities for prevention, for rapid, accurate and sensitive diagnosis and treatment of COVID-19. In this review, we focus on the nanotechnological applications and nano-based materials (i.e., personal protective equipment) to combat SARS-CoV-2 transmission, infection, organ damage and for the development of new tools for virosurveillance, diagnose and immune protection by mRNA and other nano-based vaccines. All the nano-based developed tools have allowed a historical, unprecedented, real time epidemiological surveillance and diagnosis of SARS-CoV-2 infection, at community and international levels. The nano-based technology has help to predict and detect how this Sarbecovirus is mutating and the severity of the associated COVID-19 disease, thereby assisting the administration and public health services to make decisions and measures for preparedness against the emerging variants of SARS-CoV-2 and severe or lethal COVID-19.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:10

Enthalten in:

Frontiers in bioengineering and biotechnology - 10(2022) vom: 07., Seite 1052436

Sprache:

Englisch

Beteiligte Personen:

Valenzuela-Fernández, Agustín [VerfasserIn]
Cabrera-Rodriguez, Romina [VerfasserIn]
Ciuffreda, Laura [VerfasserIn]
Perez-Yanes, Silvia [VerfasserIn]
Estevez-Herrera, Judith [VerfasserIn]
González-Montelongo, Rafaela [VerfasserIn]
Alcoba-Florez, Julia [VerfasserIn]
Trujillo-González, Rodrigo [VerfasserIn]
García-Martínez de Artola, Diego [VerfasserIn]
Gil-Campesino, Helena [VerfasserIn]
Díez-Gil, Oscar [VerfasserIn]
Lorenzo-Salazar, José M [VerfasserIn]
Flores, Carlos [VerfasserIn]
Garcia-Luis, Jonay [VerfasserIn]

Links:

Volltext

Themen:

Genome sequencing
Journal Article
Lipid nanoparticles
Modified mRNA
Nanoreagents
Personal protective equipment
Recombinant proteins
Review
Surveillance and diagnosis
Vaccines

Anmerkungen:

Date Revised 06.11.2023

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.3389/fbioe.2022.1052436

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM350194742