Clinical characteristics of COVID-19 patients who underwent tracheostomy and its effect on outcome : A retrospective observational study
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved..
BACKGROUND: The exponential rise in Coronavirus disease 2019 (COVID-19) cases has resulted in an increased number of patients requiring prolonged ventilatory support and subsequent tracheostomy. With the limited availability of literature regarding the outcomes of COVID-19 patients with tracheostomy, we attempted to study the clinical characteristics and multiple parameters affecting the outcomes in these patients.
AIM: To determine all-cause mortality following tracheostomy and its association with various risk factors in COVID-19 patients.
METHODS: This retrospective study included 73 adult COVID-19 patients admitted to the ICU between 1 April, 2020 and 30 September, 2021 who underwent tracheostomy as a result of acute respiratory failure due to COVID-19. The data collected included demographics (age, sex), comorbidities, type of oxygen support at admission, severity of COVID-19, complications, and other parameters such as admission to tracheostomy, intubation to tracheostomy, ICU stay, hospital stay, and outcome.
RESULTS: This study included 73 adult patients with an average age of 52 ± 16.67 years, of which 52% were men. The average time for admission to tracheostomy was 18.12 ± 12.98 days while intubation to tracheostomy was 11.97 ± 9 days. The mortality rate was 71.2% and 28.8% of patients were discharged alive. The mean duration of ICU and hospital stay was 25 ± 11 days and 28.21 ± 11.60 days, respectively. Greater age, severe COVID-19, mechanical ventilation, shock and acute kidney injury were associated with poor prognosis; however, early tracheostomy in intubated patients resulted in better outcomes.
CONCLUSION: Patients with severe COVID-19 requiring mechanical ventilation have a poor prognosis but patients with early tracheostomy may benefit with no added risk. We recommend that the timing of tracheostomy be decided on a case-by-case basis and a well-designed randomised controlled trial should be performed to elucidate the potential benefit of early tracheostomy in such patients.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
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| Enthalten in: |
World journal of virology - 11(2022), 6 vom: 25. Nov., Seite 477-484 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Singh, Yudhyavir [VerfasserIn] |
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| Links: |
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| Themen: |
COVID-19 |
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| Anmerkungen: |
Date Revised 10.12.2022 published: Print Citation Status PubMed-not-MEDLINE |
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| doi: |
10.5501/wjv.v11.i6.477 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM349954194 |
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| 100 | 1 | |a Singh, Yudhyavir |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Clinical characteristics of COVID-19 patients who underwent tracheostomy and its effect on outcome |b A retrospective observational study |
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| 520 | |a ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. | ||
| 520 | |a BACKGROUND: The exponential rise in Coronavirus disease 2019 (COVID-19) cases has resulted in an increased number of patients requiring prolonged ventilatory support and subsequent tracheostomy. With the limited availability of literature regarding the outcomes of COVID-19 patients with tracheostomy, we attempted to study the clinical characteristics and multiple parameters affecting the outcomes in these patients | ||
| 520 | |a AIM: To determine all-cause mortality following tracheostomy and its association with various risk factors in COVID-19 patients | ||
| 520 | |a METHODS: This retrospective study included 73 adult COVID-19 patients admitted to the ICU between 1 April, 2020 and 30 September, 2021 who underwent tracheostomy as a result of acute respiratory failure due to COVID-19. The data collected included demographics (age, sex), comorbidities, type of oxygen support at admission, severity of COVID-19, complications, and other parameters such as admission to tracheostomy, intubation to tracheostomy, ICU stay, hospital stay, and outcome | ||
| 520 | |a RESULTS: This study included 73 adult patients with an average age of 52 ± 16.67 years, of which 52% were men. The average time for admission to tracheostomy was 18.12 ± 12.98 days while intubation to tracheostomy was 11.97 ± 9 days. The mortality rate was 71.2% and 28.8% of patients were discharged alive. The mean duration of ICU and hospital stay was 25 ± 11 days and 28.21 ± 11.60 days, respectively. Greater age, severe COVID-19, mechanical ventilation, shock and acute kidney injury were associated with poor prognosis; however, early tracheostomy in intubated patients resulted in better outcomes | ||
| 520 | |a CONCLUSION: Patients with severe COVID-19 requiring mechanical ventilation have a poor prognosis but patients with early tracheostomy may benefit with no added risk. We recommend that the timing of tracheostomy be decided on a case-by-case basis and a well-designed randomised controlled trial should be performed to elucidate the potential benefit of early tracheostomy in such patients | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a ICU | |
| 650 | 4 | |a Intubation | |
| 650 | 4 | |a Mechanical ventilation | |
| 650 | 4 | |a Oxygen therapy | |
| 650 | 4 | |a Tracheostomy | |
| 700 | 1 | |a Soni, Kapil Dev |e verfasserin |4 aut | |
| 700 | 1 | |a Singh, Abhishek |e verfasserin |4 aut | |
| 700 | 1 | |a Choudhary, Nikita |e verfasserin |4 aut | |
| 700 | 1 | |a Perveen, Fahina |e verfasserin |4 aut | |
| 700 | 1 | |a Aggarwal, Richa |e verfasserin |4 aut | |
| 700 | 1 | |a Patel, Nishant |e verfasserin |4 aut | |
| 700 | 1 | |a Kumar, Shailendra |e verfasserin |4 aut | |
| 700 | 1 | |a Trikha, Anjan |e verfasserin |4 aut | |
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