Fulminant Streptococcus suis infection detected on peripheral blood smear : A case report
Copyright © 2022 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved..
Streptococcus suis, a gram-positive coccus, is recognized as an emerging zoonotic pathogen that causes serious infections in humans, such as bacterial meningitis and sepsis, with poor outcomes. The pathogen is known to be transmitted through the consumption of raw pork or occupational exposure to pigs. A previously healthy 38-year-old woman with occupational exposure to raw pork was presented to our emergency department with a clinical diagnosis of rapidly progressive septic shock. Peripheral blood smears detected chains of cocci inside granulocytes, which led to the early recognition of gram-positive cocci in short chains before the blood culture test results. Blood cultures later tested positive for S. suis serotype 2. The patient's condition deteriorated despite aggressive resuscitative measures including antibiotics, vasopressors, multiple blood transfusions, mechanical ventilation, and renal replacement therapy. Initiation of veno-arterial extracorporeal membrane oxygenation was ineffective, and the patient died 16 h after admission. The identification of bacteria in the peripheral blood smear indicated an overwhelming infection and led to the rapid recognition of bacteremia. Our report aims to raise awareness about fatal zoonotic pathogens and to promote the unique role of peripheral blood smears that could provide preliminary diagnostic information before blood culture results.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:29 |
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| Enthalten in: |
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 29(2023), 3 vom: 01. März, Seite 357-360 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Negishi, Kumiko [VerfasserIn] |
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| Links: |
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| Themen: |
Anti-Bacterial Agents |
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| Anmerkungen: |
Date Completed 30.01.2023 Date Revised 02.02.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.jiac.2022.11.012 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM349861145 |
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| 520 | |a Copyright © 2022 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved. | ||
| 520 | |a Streptococcus suis, a gram-positive coccus, is recognized as an emerging zoonotic pathogen that causes serious infections in humans, such as bacterial meningitis and sepsis, with poor outcomes. The pathogen is known to be transmitted through the consumption of raw pork or occupational exposure to pigs. A previously healthy 38-year-old woman with occupational exposure to raw pork was presented to our emergency department with a clinical diagnosis of rapidly progressive septic shock. Peripheral blood smears detected chains of cocci inside granulocytes, which led to the early recognition of gram-positive cocci in short chains before the blood culture test results. Blood cultures later tested positive for S. suis serotype 2. The patient's condition deteriorated despite aggressive resuscitative measures including antibiotics, vasopressors, multiple blood transfusions, mechanical ventilation, and renal replacement therapy. Initiation of veno-arterial extracorporeal membrane oxygenation was ineffective, and the patient died 16 h after admission. The identification of bacteria in the peripheral blood smear indicated an overwhelming infection and led to the rapid recognition of bacteremia. Our report aims to raise awareness about fatal zoonotic pathogens and to promote the unique role of peripheral blood smears that could provide preliminary diagnostic information before blood culture results | ||
| 650 | 4 | |a Case Reports | |
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| 700 | 1 | |a Sakamoto, Naoya |e verfasserin |4 aut | |
| 700 | 1 | |a Sugiyama, Kazuhiro |e verfasserin |4 aut | |
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