A Case of Nephrotic Syndrome with Bilateral Serous Retinal Detachment and Shallow Anterior Chamber Associated with Ciliary Body Edema

Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel..

Nephrotic syndrome is a disease that causes fluid retention in the body due to loss of protein in the blood, which can lead to serous retinal detachment (SRD) in the macula. We report a case of severe SRD in both eyes and angle closure due to ciliary body edema caused by nephrotic syndrome. A 57-year-old man was admitted to the Department of Nephrology in our hospital for a thorough examination of his generalized edema. He was diagnosed with nephrotic syndrome but proved to be refractory to steroid treatment. Due to distortion symptoms in both eyes on the 30th day of hospitalization, the patient was referred to our department. Best-corrected visual acuity (BCVA) was 0.8 in the right eye and 1.0 in the left eye. Slit lamp examination and anterior segmental optical coherence tomography (OCT) showed shallow anterior chambers in both eyes. Fundus and macular OCT demonstrated severe SRD in the posterior pole of both eyes. After observing the presence of hypoalbuminemia, we considered the possibility of SRD and angle closure due to ciliary edema that resulted from the leaks associated with the nephrotic syndrome. Thereafter, ocular findings improved in conjunction with systemic symptom improvements associated with ultrafiltration and low-density lipoprotein apheresis. On the 60th day of hospitalization, his BCVA improved to 1.2 in both eyes, SRD disappeared, and the anterior chamber depth normalized. This case demonstrates the importance of recognizing SRD and angle closure associated with ciliary body edema as complications linked with nephrotic syndrome.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:13

Enthalten in:

Case reports in ophthalmology - 13(2022), 3 vom: 24. Sept., Seite 949-955

Sprache:

Englisch

Beteiligte Personen:

Takai, Yasuyuki [VerfasserIn]
Sakuma, Toshiro [VerfasserIn]
Mashimo, Keitaro [VerfasserIn]
Inoue, Kenji [VerfasserIn]
Ebihara, Nobuyuki [VerfasserIn]

Links:

Volltext

Themen:

Anterior segment optical coherence tomography
Case Reports
Ciliary body edema
Nephrotic syndrome
Serous retinal detachment

Anmerkungen:

Date Revised 06.12.2022

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.1159/000527039

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM349785678