Research Progress and Future Development Potential of Oridonin in Pharmacological Activities

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In recent years, attention has increasingly focused on herbal medicines and their bioactive components attributed to their multi-target pharmacological activity and low side effects. Oridonin is a natural diterpenoid extracted from the traditional Chinese herb and is one of the main active components of Rabdosia rubescens. Modern pharmacological studies have shown that oridonin has anti-tumor, anti-bacterial, anti-inflammatory, anti-oxidant, cardiovascular protective, immunomodulatory, and other effects. Based on the published literature in recent years, we outline the pharmacological activities of oridonin, aiming to provide a theoretical basis for the design and development of new oridonin-based drugs, as well as to facilitate the process of oridonin for clinical use.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:16

Enthalten in:

Current molecular pharmacology - 16(2023), 7 vom: 14., Seite 691-706

Sprache:

Englisch

Beteiligte Personen:

Ye, Shiying [VerfasserIn]
Sun, Shaowei [VerfasserIn]
Cai, Jiye [VerfasserIn]
Jiang, Jinhuan [VerfasserIn]

Links:

Volltext

Themen:

0APJ98UCLQ
Anti-Inflammatory Agents
Anti-bacterial
Anti-inflammatory
Anti-oxidant
Anti-tumor
Antineoplastic Agents
Diterpenes
Diterpenes, Kaurane
Journal Article
Oridonin
Pharmacological activities
Research Support, Non-U.S. Gov't

Anmerkungen:

Date Completed 17.05.2023

Date Revised 19.05.2023

published: Print

Citation Status MEDLINE

doi:

10.2174/1874467216666221130163634

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM349661413