COVID-19 vaccination and recurrent anterior uveitis

A 35-year-old Asian Indian female previously diagnosed with bilateral anterior uveitis and on oral methotrexate developed bilateral anterior uveitis following first/second dose of coronavirus disease 2019 (COVID-19) vaccination. She had skipped her weekly dose of oral methotrexate following first dose of vaccination. Following the second dose, she reduced her oral methotrexate from 25 to 15 mg on her own, but did not stop like the previous occasion. She had extensive workup for her uveitis in the past with only positive severe acute respiratory syndrome coronavirus (SARS-CoV-2) antibodies. She developed unilateral anterior uveitis after she had COVID-19 in July 2022, which resolved with topical steroids and continuation of immunosuppression. This report illustrates that COVID-19 or its vaccination may presumably play a role in triggering the immune system and can cause recurrent ocular inflammation even in the absence of an extraocular inflammation.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:70

Enthalten in:

Indian journal of ophthalmology - 70(2022), 12 vom: 06. Dez., Seite 4445-4448

Sprache:

Englisch

Beteiligte Personen:

Sanjay, Srinivasan [VerfasserIn]
Yathish, G C [VerfasserIn]
Singh, Yogeshpreet [VerfasserIn]
Kawali, Ankush [VerfasserIn]
Mahendradas, Padmamalini [VerfasserIn]
Shetty, Rohit [VerfasserIn]

Links:

Volltext

Themen:

Anterior uveitis
COVID-19
COVID-19 Vaccines
Case Reports
Immunosuppression
Methotrexate
Naranjo score
Vaccination
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Anmerkungen:

Date Completed 02.12.2022

Date Revised 22.02.2023

published: Print

Citation Status MEDLINE

doi:

10.4103/ijo.IJO_1089_22

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM349660239