Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years
© 2022. The Author(s)..
Immune response induced by COVID-19 vaccine booster against delta and omicron variants was assessed in 65 adults (65-84 years old) early aftesr a first booster dose. An increase in SARS-CoV-2 neutralizing antibodies was shown in individuals not previously infected without evidence of an age-related effect, with lower increase in those infected before a single dose of primary vaccination. Of note, humoral response was observed only starting from the 5th day after the boost.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
|---|---|
| Enthalten in: |
Scientific reports - 12(2022), 1 vom: 27. Nov., Seite 20373 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Durier, Christine [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Antibodies, Neutralizing |
|---|
| Anmerkungen: |
Date Completed 29.11.2022 Date Revised 13.01.2023 published: Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1038/s41598-022-24409-w |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM34950203X |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM34950203X | ||
| 003 | DE-627 | ||
| 005 | 20231226205622.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1038/s41598-022-24409-w |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1164.xml |
| 035 | |a (DE-627)NLM34950203X | ||
| 035 | |a (NLM)36437298 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Durier, Christine |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 29.11.2022 | ||
| 500 | |a Date Revised 13.01.2023 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2022. The Author(s). | ||
| 520 | |a Immune response induced by COVID-19 vaccine booster against delta and omicron variants was assessed in 65 adults (65-84 years old) early aftesr a first booster dose. An increase in SARS-CoV-2 neutralizing antibodies was shown in individuals not previously infected without evidence of an age-related effect, with lower increase in those infected before a single dose of primary vaccination. Of note, humoral response was observed only starting from the 5th day after the boost | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 7 | |a Antibodies, Neutralizing |2 NLM | |
| 650 | 7 | |a Antibodies, Viral |2 NLM | |
| 650 | 7 | |a RNA, Messenger |2 NLM | |
| 650 | 7 | |a Viral Vaccines |2 NLM | |
| 700 | 1 | |a Ninove, Laetitia |e verfasserin |4 aut | |
| 700 | 1 | |a Lefebvre, Maeva |e verfasserin |4 aut | |
| 700 | 1 | |a Radenne, Anne |e verfasserin |4 aut | |
| 700 | 1 | |a Desaint, Corinne |e verfasserin |4 aut | |
| 700 | 1 | |a Ropers, Jacques |e verfasserin |4 aut | |
| 700 | 1 | |a Bauer, Rebecca |e verfasserin |4 aut | |
| 700 | 1 | |a Lebbah, Said |e verfasserin |4 aut | |
| 700 | 1 | |a Carette, Diane |e verfasserin |4 aut | |
| 700 | 1 | |a Lachatre, Marie |e verfasserin |4 aut | |
| 700 | 1 | |a Lecompte, Anne-Sophie |e verfasserin |4 aut | |
| 700 | 1 | |a Deplanque, Dominique |e verfasserin |4 aut | |
| 700 | 1 | |a Botelho-Nevers, Elisabeth |e verfasserin |4 aut | |
| 700 | 1 | |a Conrad, Anne |e verfasserin |4 aut | |
| 700 | 1 | |a Dussol, Bertrand |e verfasserin |4 aut | |
| 700 | 1 | |a Maakaroun-Vermesse, Zoha |e verfasserin |4 aut | |
| 700 | 1 | |a Melica, Giovanna |e verfasserin |4 aut | |
| 700 | 1 | |a Nicolas, Jean-François |e verfasserin |4 aut | |
| 700 | 1 | |a Verdon, Renaud |e verfasserin |4 aut | |
| 700 | 1 | |a Kiladjian, Jacques |e verfasserin |4 aut | |
| 700 | 1 | |a Loubet, Paul |e verfasserin |4 aut | |
| 700 | 1 | |a Schmidt-Mutter, Catherine |e verfasserin |4 aut | |
| 700 | 1 | |a Dualé, Christian |e verfasserin |4 aut | |
| 700 | 1 | |a Ansart, Séverine |e verfasserin |4 aut | |
| 700 | 1 | |a Priet, Stéphane |e verfasserin |4 aut | |
| 700 | 1 | |a Levier, Axel |e verfasserin |4 aut | |
| 700 | 1 | |a Molino, Diana |e verfasserin |4 aut | |
| 700 | 1 | |a Vieillard, Louis-Victorien |e verfasserin |4 aut | |
| 700 | 1 | |a Parfait, Béatrice |e verfasserin |4 aut | |
| 700 | 1 | |a Lelièvre, Jean-Daniel |e verfasserin |4 aut | |
| 700 | 1 | |a Tartour, Eric |e verfasserin |4 aut | |
| 700 | 1 | |a de Lamballerie, Xavier |e verfasserin |4 aut | |
| 700 | 1 | |a Launay, Odile |e verfasserin |4 aut | |
| 700 | 0 | |a ANRS0002S CoviCompareP Group |e verfasserin |4 aut | |
| 700 | 0 | |a AP-HP CoviCompareM Group |e verfasserin |4 aut | |
| 700 | 0 | |a Biological resource centers |e verfasserin |4 aut | |
| 700 | 0 | |a Laboratories |e verfasserin |4 aut | |
| 700 | 0 | |a Trial coordination |e verfasserin |4 aut | |
| 700 | 0 | |a Sponsor |e verfasserin |4 aut | |
| 700 | 0 | |a Scientific Committee |e verfasserin |4 aut | |
| 700 | 1 | |a Mchantaf, Gilbert |e investigator |4 oth | |
| 700 | 1 | |a Imbert-Marcille, Berthe-Marie |e investigator |4 oth | |
| 700 | 1 | |a Montagne, Samantha |e investigator |4 oth | |
| 700 | 1 | |a Ghaleh-Marzban, Bijan |e investigator |4 oth | |
| 700 | 1 | |a Traverse-Glehen, Alexandra |e investigator |4 oth | |
| 700 | 1 | |a Vivien, Denis |e investigator |4 oth | |
| 700 | 1 | |a Cassinat, Bruno |e investigator |4 oth | |
| 700 | 1 | |a Evrard, Alexandre |e investigator |4 oth | |
| 700 | 1 | |a Metzger, Catherine |e investigator |4 oth | |
| 700 | 1 | |a Lessinger, Jean-Marc |e investigator |4 oth | |
| 700 | 1 | |a Billing, Michel |e investigator |4 oth | |
| 700 | 1 | |a Berger, Marc |e investigator |4 oth | |
| 700 | 1 | |a Leroyer, Christophe |e investigator |4 oth | |
| 700 | 1 | |a Tartour, Eric |e investigator |4 oth | |
| 700 | 1 | |a Appay, Victor |e investigator |4 oth | |
| 700 | 1 | |a Batteux, Frédéric |e investigator |4 oth | |
| 700 | 1 | |a Combadière, Béhazine |e investigator |4 oth | |
| 700 | 1 | |a Gorochov, Guy |e investigator |4 oth | |
| 700 | 1 | |a Paul, Stéphane |e investigator |4 oth | |
| 700 | 1 | |a Van Der Werf, Sylvie |e investigator |4 oth | |
| 700 | 1 | |a Eberhardt, Christiane S |e investigator |4 oth | |
| 700 | 1 | |a Siegrist, Claire-Anne |e investigator |4 oth | |
| 700 | 1 | |a Cogné, Michel |e investigator |4 oth | |
| 700 | 1 | |a Pellegrin, Isabelle |e investigator |4 oth | |
| 700 | 1 | |a Eloit, Marc |e investigator |4 oth | |
| 700 | 1 | |a Netzer, Emmanuelle |e investigator |4 oth | |
| 700 | 1 | |a Resch, Martine |e investigator |4 oth | |
| 700 | 1 | |a Saouzanet, Marine |e investigator |4 oth | |
| 700 | 1 | |a Meyer, Laurence |e investigator |4 oth | |
| 700 | 1 | |a Bonneton, Marion |e investigator |4 oth | |
| 700 | 1 | |a Tardieu, Raphaelle |e investigator |4 oth | |
| 700 | 1 | |a Le Mestre, Soizic |e investigator |4 oth | |
| 700 | 1 | |a Jancrey-Laval, Solange |e investigator |4 oth | |
| 700 | 1 | |a Petrov-Sanchez, Ventzislava |e investigator |4 oth | |
| 700 | 1 | |a Rosenthal, Eric |e investigator |4 oth | |
| 700 | 1 | |a Yazdanpanah, Yazdan |e investigator |4 oth | |
| 700 | 1 | |a Olive, Daniel |e investigator |4 oth | |
| 700 | 1 | |a Tardieu, Raphaelle |e investigator |4 oth | |
| 700 | 1 | |a Petrov-Sanchez, Ventzislava |e investigator |4 oth | |
| 700 | 1 | |a Bouakane, Amel |e investigator |4 oth | |
| 700 | 1 | |a Rieux, Veronique |e investigator |4 oth | |
| 700 | 1 | |a Madelaine, Claire |e investigator |4 oth | |
| 700 | 1 | |a Lemestre, Soizic |e investigator |4 oth | |
| 700 | 1 | |a Diallo, Alpha |e investigator |4 oth | |
| 700 | 1 | |a Lancrey-Javal, Solange |e investigator |4 oth | |
| 700 | 1 | |a Meyer, Laurence |e investigator |4 oth | |
| 700 | 1 | |a Netzer, Emmanuelle |e investigator |4 oth | |
| 700 | 1 | |a Saouzanet, Marine |e investigator |4 oth | |
| 700 | 1 | |a Valour, Florent |e investigator |4 oth | |
| 700 | 1 | |a Dussol, Bertrand |e investigator |4 oth | |
| 700 | 1 | |a Melica, Giovanna |e investigator |4 oth | |
| 700 | 1 | |a Mchantaf, Gilbert |e investigator |4 oth | |
| 700 | 1 | |a Hisbergues, Michael |e investigator |4 oth | |
| 700 | 1 | |a Bertholon, Frédérique |e investigator |4 oth | |
| 700 | 1 | |a Icard, Vinca |e investigator |4 oth | |
| 700 | 1 | |a de Sandre-Giovannoli, Annachiara |e investigator |4 oth | |
| 700 | 1 | |a Ghaleh-Marzban, Bijan |e investigator |4 oth | |
| 700 | 1 | |a Appay, Victor |e investigator |4 oth | |
| 700 | 1 | |a Batteux, Frédéric |e investigator |4 oth | |
| 700 | 1 | |a Combadière, Béhazine |e investigator |4 oth | |
| 700 | 1 | |a Gorochov, Guy |e investigator |4 oth | |
| 700 | 1 | |a Paul, Stéphane |e investigator |4 oth | |
| 700 | 1 | |a Van Der Werf, Sylvie |e investigator |4 oth | |
| 700 | 1 | |a Eberhardt, Christiane S |e investigator |4 oth | |
| 700 | 1 | |a Siegrist, Claire-Anne |e investigator |4 oth | |
| 700 | 1 | |a Cogné, Michel |e investigator |4 oth | |
| 700 | 1 | |a Dropy, Margot |e investigator |4 oth | |
| 700 | 1 | |a Bouchama, Fatiha |e investigator |4 oth | |
| 700 | 1 | |a Thamri, Mehdi |e investigator |4 oth | |
| 700 | 1 | |a Lebbah, Saïd |e investigator |4 oth | |
| 700 | 1 | |a Bonneton, Marion |e investigator |4 oth | |
| 700 | 1 | |a Azimi, Shorheh |e investigator |4 oth | |
| 700 | 1 | |a Parfait, Beatrice |e investigator |4 oth | |
| 700 | 1 | |a Appay, Victor |e investigator |4 oth | |
| 700 | 1 | |a Batteux, Frédéric |e investigator |4 oth | |
| 700 | 1 | |a Combadière, Béhazine |e investigator |4 oth | |
| 700 | 1 | |a Gorochov, Guy |e investigator |4 oth | |
| 700 | 1 | |a Paul, Stéphane |e investigator |4 oth | |
| 700 | 1 | |a Van Der Werf, Sylvie |e investigator |4 oth | |
| 700 | 1 | |a Siegrist, Claire-Anne |e investigator |4 oth | |
| 700 | 1 | |a Cogné, Michel |e investigator |4 oth | |
| 700 | 1 | |a Valour, Florent |e investigator |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |t Scientific reports |d 2011 |g 12(2022), 1 vom: 27. Nov., Seite 20373 |w (DE-627)NLM215703936 |x 2045-2322 |7 nnns |
| 773 | 1 | 8 | |g volume:12 |g year:2022 |g number:1 |g day:27 |g month:11 |g pages:20373 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1038/s41598-022-24409-w |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 12 |j 2022 |e 1 |b 27 |c 11 |h 20373 | ||