Autopsy Case Report of Severe COVID-19 Pneumonia at a General Municipal Hospital
We present the autopsy procedure and findings of severe coronavirus disease 2019 (COVID-19) pneumonia in an 85-year-old man. The patient required intubation immediately after admission for severe COVID-19 pneumonia. He had severe hypoxia that did not improve despite treatment with remdesivir, corticosteroids, and appropriate mechanical ventilation. On day 13, the patient developed sudden hypercapnia. His renal dysfunction subsequently worsened and became associated with hyperkalemia, and he passed away on day 15. An autopsy was performed to clarify the cause of the hypercapnic hypoxia. None of the medical personnel involved in the autopsy developed symptoms of COVID-19. Histologic examination showed various stages of diffuse alveolar damage throughout the lungs, with intra-alveolar hemorrhage in the upper zones. Microscopic examination of the kidneys revealed acute tubular necrosis. There was no significant systemic thrombosis. The autopsy findings were consistent with those typical of COVID-19.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:47 |
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| Enthalten in: |
The Tokai journal of experimental and clinical medicine - 47(2022), 4 vom: 20. Dez., Seite 162-164 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Iketani, Yuri [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 25.11.2022 Date Revised 25.11.2022 published: Electronic Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM349336210 |
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| 520 | |a We present the autopsy procedure and findings of severe coronavirus disease 2019 (COVID-19) pneumonia in an 85-year-old man. The patient required intubation immediately after admission for severe COVID-19 pneumonia. He had severe hypoxia that did not improve despite treatment with remdesivir, corticosteroids, and appropriate mechanical ventilation. On day 13, the patient developed sudden hypercapnia. His renal dysfunction subsequently worsened and became associated with hyperkalemia, and he passed away on day 15. An autopsy was performed to clarify the cause of the hypercapnic hypoxia. None of the medical personnel involved in the autopsy developed symptoms of COVID-19. Histologic examination showed various stages of diffuse alveolar damage throughout the lungs, with intra-alveolar hemorrhage in the upper zones. Microscopic examination of the kidneys revealed acute tubular necrosis. There was no significant systemic thrombosis. The autopsy findings were consistent with those typical of COVID-19 | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Naruke, Takashi |e verfasserin |4 aut | |
| 700 | 1 | |a Umebachi, Rimako |e verfasserin |4 aut | |
| 700 | 1 | |a Kameda, Ryo |e verfasserin |4 aut | |
| 700 | 1 | |a Yuge, Masaru |e verfasserin |4 aut | |
| 700 | 1 | |a Matsuda, Motoi |e verfasserin |4 aut | |
| 700 | 1 | |a Ako, Junya |e verfasserin |4 aut | |
| 700 | 1 | |a Kawaguchi, Takeo |e verfasserin |4 aut | |
| 700 | 1 | |a Morita, Seiji |e verfasserin |4 aut | |
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