Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth.) Valeton
Two new bisanthraquinones, glabraquinone A and B (1-2) were isolated from the root of Prismatomeris glabra (Korth.) Valeton. In addition to the new glabraquinones, six known anthraquinones, that is, 1-hydroxy-2-methoxy-6-methylanthraquinone (3), 1,2-dimethoxy-7-methylanthraquinone (4), lucidin (5), nordamnacanthal (6), damnacanthal (7) and 2-carboxaldehyde-3-hydroxyanthraquinone (8)) and an aromatic compound, that is, catechol diethyl ether (9) were isolated and characterized in this study. Compounds 1, 4 and 9 showed mild activity, reducing N2A cell viability to 77%, 82% and 77%, respectively, in anti-neuroblastoma assay.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2024 |
|---|---|
| Erschienen: |
2024 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:38 |
|---|---|
| Enthalten in: |
Natural product research - 38(2024), 8 vom: 25. März, Seite 1406-1413 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Primus, Phoebe Sussana [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
1-hydroxy-2-methylanthraquinone |
|---|
| Anmerkungen: |
Date Completed 25.03.2024 Date Revised 25.03.2024 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1080/14786419.2022.2147932 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM349295484 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM349295484 | ||
| 003 | DE-627 | ||
| 005 | 20240325234131.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1080/14786419.2022.2147932 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1346.xml |
| 035 | |a (DE-627)NLM349295484 | ||
| 035 | |a (NLM)36416441 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Primus, Phoebe Sussana |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth.) Valeton |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 25.03.2024 | ||
| 500 | |a Date Revised 25.03.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Two new bisanthraquinones, glabraquinone A and B (1-2) were isolated from the root of Prismatomeris glabra (Korth.) Valeton. In addition to the new glabraquinones, six known anthraquinones, that is, 1-hydroxy-2-methoxy-6-methylanthraquinone (3), 1,2-dimethoxy-7-methylanthraquinone (4), lucidin (5), nordamnacanthal (6), damnacanthal (7) and 2-carboxaldehyde-3-hydroxyanthraquinone (8)) and an aromatic compound, that is, catechol diethyl ether (9) were isolated and characterized in this study. Compounds 1, 4 and 9 showed mild activity, reducing N2A cell viability to 77%, 82% and 77%, respectively, in anti-neuroblastoma assay | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Prismatomeris glabra (Korth.) Valeton | |
| 650 | 4 | |a Rubiaceae | |
| 650 | 4 | |a anthraquinones | |
| 650 | 4 | |a anti-neuroblastoma | |
| 650 | 4 | |a bisanthraquinones | |
| 650 | 4 | |a glabraquinones | |
| 650 | 7 | |a Anthraquinones |2 NLM | |
| 650 | 7 | |a 2-methylanthraquinone |2 NLM | |
| 650 | 7 | |a Q9P233HWAJ |2 NLM | |
| 650 | 7 | |a 1-hydroxy-2-methylanthraquinone |2 NLM | |
| 700 | 1 | |a Wu, Carol Hsin-Yi |e verfasserin |4 aut | |
| 700 | 1 | |a Kao, Chai-Lin |e verfasserin |4 aut | |
| 700 | 1 | |a Choo, Yeun-Mun |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Natural product research |d 2003 |g 38(2024), 8 vom: 25. März, Seite 1406-1413 |w (DE-627)NLM124466303 |x 1478-6427 |7 nnns |
| 773 | 1 | 8 | |g volume:38 |g year:2024 |g number:8 |g day:25 |g month:03 |g pages:1406-1413 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1080/14786419.2022.2147932 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 38 |j 2024 |e 8 |b 25 |c 03 |h 1406-1413 | ||