The efficacy of platelet-rich plasma in osseous foot and ankle pathology : a review
The purpose of this review is to develop evidence-based practices for the use of platelet-rich plasma (PRP) to treat osseous pathologies of the lower extremity. There is moderate high-quality evidence to support the efficacy of PRP as a surgical augment to microfracture in osteochondral lesions of the talus (OLT). The literature supports a conceivable positive impact on bony union and osseous healing. There is insufficient evidence to support PRP injections in the conservative management of OLT or symptomatic ankle osteoarthritis. PRP may serve as a viable treatment method in the surgical augmentation of microfracture surgery in OLT and has promise for increasing bony union following surgical operations. Further high-quality, comparative studies with longer clinical follow-up are required.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:18 |
|---|---|
| Enthalten in: |
Regenerative medicine - 18(2023), 1 vom: 07. Jan., Seite 73-84 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Johnson, Lindsey G [VerfasserIn] |
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| Links: |
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| Themen: |
Ankle osteoarthritis |
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| Anmerkungen: |
Date Completed 15.12.2022 Date Revised 22.12.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.2217/rme-2022-0056 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM348958803 |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The purpose of this review is to develop evidence-based practices for the use of platelet-rich plasma (PRP) to treat osseous pathologies of the lower extremity. There is moderate high-quality evidence to support the efficacy of PRP as a surgical augment to microfracture in osteochondral lesions of the talus (OLT). The literature supports a conceivable positive impact on bony union and osseous healing. There is insufficient evidence to support PRP injections in the conservative management of OLT or symptomatic ankle osteoarthritis. PRP may serve as a viable treatment method in the surgical augmentation of microfracture surgery in OLT and has promise for increasing bony union following surgical operations. Further high-quality, comparative studies with longer clinical follow-up are required | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a platelet-rich plasma | |
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| 700 | 1 | |a Abar, Bijan |e verfasserin |4 aut | |
| 700 | 1 | |a Fletcher, Amanda N |e verfasserin |4 aut | |
| 700 | 1 | |a Adams, Samuel B |e verfasserin |4 aut | |
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