Association between driving a car and retention of brain volume in Japanese older adults
Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved..
BACKGROUND: Driving cessation is a major negative life event that has been associated with a decline in health conditions including dementia. The increase in activity owing to the expansion of life space is a possible explanation for the positive relationship between driving and brain health. The present study examined the association between driving, life space, and structural brain volume in older individuals.
METHODS: High-resolution magnetic resonance imaging was employed to examine the brain volume in 1063 older adults. Participants were classified as non-drivers, those who drove <7 days a week, and everyday drivers. They were further classified into a non-driving group, an active group (drove 10 km at least once a week), and a less-active group (drove 10 km less than once a week).
RESULTS: The hippocampal volume was greater in drivers than in non-drivers. Occipital cortex volume was greater in low-frequency drivers than in non-drivers and high-frequency drivers. Active drivers exhibited larger temporal cortex volumes than less-active drivers, larger cingulate cortex volumes than non-drivers and less-active drivers, and larger hippocampal volumes than non-drivers.
CONCLUSION: Driving was associated with hippocampal brain atrophy attenuation, with active drivers exhibiting decreased brain atrophy in the temporal and cingulate cortices.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:171 |
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| Enthalten in: |
Experimental gerontology - 171(2023) vom: 20. Jan., Seite 112010 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Shimada, Hiroyuki [VerfasserIn] |
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| Links: |
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| Themen: |
Brain atrophy |
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| Anmerkungen: |
Date Completed 16.12.2022 Date Revised 21.12.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.exger.2022.112010 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM34850117X |
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| 245 | 1 | 0 | |a Association between driving a car and retention of brain volume in Japanese older adults |
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| 500 | |a Date Completed 16.12.2022 | ||
| 500 | |a Date Revised 21.12.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved. | ||
| 520 | |a BACKGROUND: Driving cessation is a major negative life event that has been associated with a decline in health conditions including dementia. The increase in activity owing to the expansion of life space is a possible explanation for the positive relationship between driving and brain health. The present study examined the association between driving, life space, and structural brain volume in older individuals | ||
| 520 | |a METHODS: High-resolution magnetic resonance imaging was employed to examine the brain volume in 1063 older adults. Participants were classified as non-drivers, those who drove <7 days a week, and everyday drivers. They were further classified into a non-driving group, an active group (drove 10 km at least once a week), and a less-active group (drove 10 km less than once a week) | ||
| 520 | |a RESULTS: The hippocampal volume was greater in drivers than in non-drivers. Occipital cortex volume was greater in low-frequency drivers than in non-drivers and high-frequency drivers. Active drivers exhibited larger temporal cortex volumes than less-active drivers, larger cingulate cortex volumes than non-drivers and less-active drivers, and larger hippocampal volumes than non-drivers | ||
| 520 | |a CONCLUSION: Driving was associated with hippocampal brain atrophy attenuation, with active drivers exhibiting decreased brain atrophy in the temporal and cingulate cortices | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Brain atrophy | |
| 650 | 4 | |a Cingulate cortex | |
| 650 | 4 | |a Driving | |
| 650 | 4 | |a Hippocampus | |
| 650 | 4 | |a Temporal cortex | |
| 700 | 1 | |a Bae, Seongryu |e verfasserin |4 aut | |
| 700 | 1 | |a Harada, Kenji |e verfasserin |4 aut | |
| 700 | 1 | |a Makino, Keitaro |e verfasserin |4 aut | |
| 700 | 1 | |a Chiba, Ippei |e verfasserin |4 aut | |
| 700 | 1 | |a Katayama, Osamu |e verfasserin |4 aut | |
| 700 | 1 | |a Lee, Sangyoon |e verfasserin |4 aut | |
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