Demographics and Outcomes of Initial Phase of COVID-19 Medicines Delivery Units Across 4 UK Centers During Peak B1.1.529 Omicron Epidemic : A Service Evaluation
© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America..
Background: COVID-19 medicines delivery units (CMDU) were established in late December 2021 to deliver early antiviral therapy to patients classified as at risk with the aim of preventing hospitalization.
Methods: We performed a service evaluation at 4 CMDUs in England. We assessed demographics and triage outcomes of CMDU referral, uptake of antiviral therapy, and the rate of subsequent hospitalizations within 2 weeks of CMDU referral.
Results: Over a 3-week period, 4788 patients were referred and 3989 were ultimately assessed by a CMDU. Overall, 832 of the patients referred (17%) were judged eligible for treatment and 628 (13%) were ultimately prescribed an antiviral agent. The overall rate of admission within 14 days was 1%. Patients who were admitted were significantly older than those who did not require hospitalization. Of patients prescribed molnupiravir and sotrovimab, 1.8% and 3.2%, respectively, were admitted.
Conclusions: There was a high volume of referrals to CMDU service during the initial surge of the Omicron wave in the United Kingdom. A minority of patients were judged to be eligible for therapy. In a highly vaccinated population, the overall hospitalization rate was low.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:9 |
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| Enthalten in: |
Open forum infectious diseases - 9(2022), 10 vom: 31. Okt., Seite ofac527 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Brown, Michael [VerfasserIn] |
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| Anmerkungen: |
Date Revised 21.02.2024 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1093/ofid/ofac527 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 245 | 1 | 0 | |a Demographics and Outcomes of Initial Phase of COVID-19 Medicines Delivery Units Across 4 UK Centers During Peak B1.1.529 Omicron Epidemic |b A Service Evaluation |
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| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. | ||
| 520 | |a Background: COVID-19 medicines delivery units (CMDU) were established in late December 2021 to deliver early antiviral therapy to patients classified as at risk with the aim of preventing hospitalization | ||
| 520 | |a Methods: We performed a service evaluation at 4 CMDUs in England. We assessed demographics and triage outcomes of CMDU referral, uptake of antiviral therapy, and the rate of subsequent hospitalizations within 2 weeks of CMDU referral | ||
| 520 | |a Results: Over a 3-week period, 4788 patients were referred and 3989 were ultimately assessed by a CMDU. Overall, 832 of the patients referred (17%) were judged eligible for treatment and 628 (13%) were ultimately prescribed an antiviral agent. The overall rate of admission within 14 days was 1%. Patients who were admitted were significantly older than those who did not require hospitalization. Of patients prescribed molnupiravir and sotrovimab, 1.8% and 3.2%, respectively, were admitted | ||
| 520 | |a Conclusions: There was a high volume of referrals to CMDU service during the initial surge of the Omicron wave in the United Kingdom. A minority of patients were judged to be eligible for therapy. In a highly vaccinated population, the overall hospitalization rate was low | ||
| 650 | 4 | |a Journal Article | |
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| 700 | 1 | |a Qureshi, Azka |e verfasserin |4 aut | |
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| 700 | 1 | |a Drury, Katie |e verfasserin |4 aut | |
| 700 | 1 | |a Gahir, Joshua |e verfasserin |4 aut | |
| 700 | 1 | |a Simpson, Tom |e verfasserin |4 aut | |
| 700 | 1 | |a Newman, Thomas |e verfasserin |4 aut | |
| 700 | 1 | |a Adams, Kate |e verfasserin |4 aut | |
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| 700 | 1 | |a Cole, Joby |e verfasserin |4 aut | |
| 700 | 1 | |a Easom, Nicholas |e verfasserin |4 aut | |
| 700 | 1 | |a Goodman, Anna L |e verfasserin |4 aut | |
| 700 | 1 | |a Marks, Michael |e verfasserin |4 aut | |
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