Native heart valve thrombosis associated with COVID-19 - a report of 4 cases
© 2022 MEDPRESS..
Native heart valve thrombosis (NHVT) is a rare valvular pathology, usually associated with prothrombotic state or disturbed intracardiac blood flow related to structural valve abnormalities. While different venous and arterial thromboembolic complications of COVID-19 have been widely described, so far NHVT has not been reported in the context of the disease. The authors describe 4 cases of NHVT associated with COVID-19, revealed on aortic, mitral (2 patients) and tricuspid valve. In a 29-yearold male with mild pneumonia, large thrombus developed on bicuspid aortic valve (BAV), which resulted in fatal brain emboli. In a 76-yearold male with a history of rheumatoid arthritis (RA) being in a recovery period after COVID-19, central retinal artery occlusion (CRAO) was the first sign of mitral valve thrombus, which disappeared after 3 weeks, during apixaban use. Such therapy was also successful in a 46-yearold female with multiple cardiovascular risk factors in whom mitral valve thrombus was found in a routine echocardiography after she got COVID-19 the third time. In a 75-year-old man with moderate COVID-19 pneumonia and bacterial coinfection, coexistent transient focal LV dysfunction and tricuspid valve thrombus were observed. The patient was treated with apixaban as well; however, in this case only reduction in the thrombus size was seen after 4 months therapy. The authors indicate that in patients with COVID-19 and NHVT, other prothrombotic conditions can usually be found. This complication may involve different valves and occur irrespective of COVID-19 severity. Interdisciplinary evaluation of such patients is necessary.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:50 |
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| Enthalten in: |
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego - 50(2022), 299 vom: 21. Okt., Seite 312-317 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Elikowski, Waldemar [VerfasserIn] |
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| Themen: |
Anticoagulation |
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| Anmerkungen: |
Date Completed 27.10.2022 Date Revised 27.10.2022 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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NLM347975615 |
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| 520 | |a Native heart valve thrombosis (NHVT) is a rare valvular pathology, usually associated with prothrombotic state or disturbed intracardiac blood flow related to structural valve abnormalities. While different venous and arterial thromboembolic complications of COVID-19 have been widely described, so far NHVT has not been reported in the context of the disease. The authors describe 4 cases of NHVT associated with COVID-19, revealed on aortic, mitral (2 patients) and tricuspid valve. In a 29-yearold male with mild pneumonia, large thrombus developed on bicuspid aortic valve (BAV), which resulted in fatal brain emboli. In a 76-yearold male with a history of rheumatoid arthritis (RA) being in a recovery period after COVID-19, central retinal artery occlusion (CRAO) was the first sign of mitral valve thrombus, which disappeared after 3 weeks, during apixaban use. Such therapy was also successful in a 46-yearold female with multiple cardiovascular risk factors in whom mitral valve thrombus was found in a routine echocardiography after she got COVID-19 the third time. In a 75-year-old man with moderate COVID-19 pneumonia and bacterial coinfection, coexistent transient focal LV dysfunction and tricuspid valve thrombus were observed. The patient was treated with apixaban as well; however, in this case only reduction in the thrombus size was seen after 4 months therapy. The authors indicate that in patients with COVID-19 and NHVT, other prothrombotic conditions can usually be found. This complication may involve different valves and occur irrespective of COVID-19 severity. Interdisciplinary evaluation of such patients is necessary | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a anticoagulation | |
| 650 | 4 | |a apixaban | |
| 650 | 4 | |a native heart valve thrombosis | |
| 700 | 1 | |a Fertała, Natalia |e verfasserin |4 aut | |
| 700 | 1 | |a Zawodna-Marszałek, Magdalena |e verfasserin |4 aut | |
| 700 | 1 | |a Skrzywanek, Paweł |e verfasserin |4 aut | |
| 700 | 1 | |a Łazowski, Stanisław |e verfasserin |4 aut | |
| 700 | 1 | |a Kurzawa, Aneta |e verfasserin |4 aut | |
| 700 | 1 | |a Szczęśniewski, Patryk |e verfasserin |4 aut | |
| 700 | 1 | |a Gaca-Wysocka, Magdalena |e verfasserin |4 aut | |
| 700 | 1 | |a Sokołowski, Krzysztof |e verfasserin |4 aut | |
| 700 | 1 | |a Żytkiewicz, Marcin |e verfasserin |4 aut | |
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