Prophylactic Drain Versus No Drain in Curative Gastric Cancer Surgery-A Randomized Controlled Trial
© 2022. The Society for Surgery of the Alimentary Tract..
BACKGROUND: The adoption of enhanced recovery after surgery protocols has questioned the placement of prophylactic drain after curative gastrectomy. A 2015 Cochrane meta-analysis did not find convincing evidence of routine drain placement in gastrectomy, but the quality of evidence was questioned. The present study compared short-term outcomes of prophylactic drain placement versus no drain in gastrectomy.
METHODOLOGY: The study is a prospective, non-inferiority, and randomized controlled trial. Histologically proven adenocarcinoma of the stomach undergoing curative gastrectomy with D2 lymphadenectomy was included in the study. Randomization was done intra-operatively. The primary outcome was a postoperative hospital stay. Secondary outcomes included the return of bowel function, achieving adequate enteral feeding, re-surgery, morbidity, and mortality.
RESULTS: One hundred fifty-seven patients were registered, of which 108 patients underwent curative surgery, and were randomized to 54 patients in each group. The median age was 55 years (range: 23-78) and 58.5 years (range: 35-80) in the drain and no drain group. No significant difference was noticed in primary or secondary outcomes in both groups.
CONCLUSION: Avoid placing a prophylactic drain is not inferior to drain placement following gastrectomy with D2 lymphadenectomy for stomach adenocarcinoma. So, routine prophylactic drain placement can be avoided.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:26 |
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| Enthalten in: |
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 26(2022), 12 vom: 24. Dez., Seite 2470-2476 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Muduly, Dillip Kumar [VerfasserIn] |
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| Links: |
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| Themen: |
Drain |
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| Anmerkungen: |
Date Completed 22.11.2022 Date Revised 13.02.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1007/s11605-022-05480-0 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM347936911 |
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| 500 | |a Date Revised 13.02.2024 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2022. The Society for Surgery of the Alimentary Tract. | ||
| 520 | |a BACKGROUND: The adoption of enhanced recovery after surgery protocols has questioned the placement of prophylactic drain after curative gastrectomy. A 2015 Cochrane meta-analysis did not find convincing evidence of routine drain placement in gastrectomy, but the quality of evidence was questioned. The present study compared short-term outcomes of prophylactic drain placement versus no drain in gastrectomy | ||
| 520 | |a METHODOLOGY: The study is a prospective, non-inferiority, and randomized controlled trial. Histologically proven adenocarcinoma of the stomach undergoing curative gastrectomy with D2 lymphadenectomy was included in the study. Randomization was done intra-operatively. The primary outcome was a postoperative hospital stay. Secondary outcomes included the return of bowel function, achieving adequate enteral feeding, re-surgery, morbidity, and mortality | ||
| 520 | |a RESULTS: One hundred fifty-seven patients were registered, of which 108 patients underwent curative surgery, and were randomized to 54 patients in each group. The median age was 55 years (range: 23-78) and 58.5 years (range: 35-80) in the drain and no drain group. No significant difference was noticed in primary or secondary outcomes in both groups | ||
| 520 | |a CONCLUSION: Avoid placing a prophylactic drain is not inferior to drain placement following gastrectomy with D2 lymphadenectomy for stomach adenocarcinoma. So, routine prophylactic drain placement can be avoided | ||
| 650 | 4 | |a Meta-Analysis | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Drain | |
| 650 | 4 | |a Gastrectomy | |
| 650 | 4 | |a Gastric cancer | |
| 650 | 4 | |a Hospital stay | |
| 650 | 4 | |a Morbidity | |
| 700 | 1 | |a Imaduddin, Mohammed |e verfasserin |4 aut | |
| 700 | 1 | |a Sultania, Mahesh |e verfasserin |4 aut | |
| 700 | 1 | |a Houghton, Tim |e verfasserin |4 aut | |
| 700 | 1 | |a G, Pavan Kumar C |e verfasserin |4 aut | |
| 700 | 1 | |a Rao, P Bhaskar |e verfasserin |4 aut | |
| 700 | 1 | |a Mitra, Jayanta Kumar |e verfasserin |4 aut | |
| 700 | 1 | |a Behera, Bikram Kishore |e verfasserin |4 aut | |
| 700 | 1 | |a Mohakud, Sudipta |e verfasserin |4 aut | |
| 700 | 1 | |a Kar, Madhabananda |e verfasserin |4 aut | |
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