Evaluating and mitigating the potential indirect effect of COVID-19 on control programmes for seven neglected tropical diseases : a modelling study
Copyright © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. Published by Elsevier Ltd.. All rights reserved..
BACKGROUND: In line with movement restrictions and physical distancing essential for the control of the COVID-19 pandemic, WHO recommended postponement of all neglected tropical disease (NTD) control activities that involve community-based surveys, active case finding, and mass drug administration in April, 2020. Following revised guidance later in 2020, and after interruptions to NTD programmes of varying lengths, NTD programmes gradually restarted in the context of an ongoing pandemic. However, ongoing challenges and service gaps have been reported. This study aimed to evaluate the potential effect of the programmatic interruptions and strategies to mitigate this effect.
METHODS: For seven NTDs, namely soil-transmitted helminths, schistosomiasis, lymphatic filariasis, onchocerciasis, trachoma, visceral leishmaniasis, and human African trypanosomiasis, we used mathematical transmission models to simulate the effect of programme interruptions on the dynamics of each of these diseases in different endemic settings. We also explored the potential benefit of implementing mitigation strategies, primarily in terms of minimising the delays to control targets.
FINDINGS: We show that the effect of the COVID-19-induced interruption in terms of delay to achieving elimination goals might in some cases be much longer than the duration of the interruption. For schistosomiasis, onchocerciasis, trachoma, and visceral leishmaniasis, a mean delay of 2-3 years for a 1-year interruption is predicted in areas of highest prevalence. We also show that these delays can largely be mitigated by measures such as additional mass drug administration or enhanced case-finding.
INTERPRETATION: The COVID-19 pandemic has brought infectious disease control to the forefront of global consciousness. It is essential that the NTDs, so long neglected in terms of research and financial support, are not overlooked, and remain a priority in health service planning and funding.
FUNDING: Bill & Melinda Gates Foundation, Medical Research Council, and the UK Foreign, Commonwealth & Development Office.
| Errataetall: |
CommentIn: Lancet Glob Health. 2022 Nov;10(11):e1541-e1542. - PMID 36240812 |
|---|---|
| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
|---|---|
| Enthalten in: |
The Lancet. Global health - 10(2022), 11 vom: 01. Nov., Seite e1600-e1611 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Borlase, Anna [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 18.10.2022 Date Revised 12.04.2023 published: Print CommentIn: Lancet Glob Health. 2022 Nov;10(11):e1541-e1542. - PMID 36240812 Citation Status MEDLINE |
|---|
| doi: |
10.1016/S2214-109X(22)00360-6 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM347558585 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM347558585 | ||
| 003 | DE-627 | ||
| 005 | 20231226034117.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/S2214-109X(22)00360-6 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1158.xml |
| 035 | |a (DE-627)NLM347558585 | ||
| 035 | |a (NLM)36240827 | ||
| 035 | |a (PII)S2214-109X(22)00360-6 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Borlase, Anna |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Evaluating and mitigating the potential indirect effect of COVID-19 on control programmes for seven neglected tropical diseases |b a modelling study |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 18.10.2022 | ||
| 500 | |a Date Revised 12.04.2023 | ||
| 500 | |a published: Print | ||
| 500 | |a CommentIn: Lancet Glob Health. 2022 Nov;10(11):e1541-e1542. - PMID 36240812 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. Published by Elsevier Ltd.. All rights reserved. | ||
| 520 | |a BACKGROUND: In line with movement restrictions and physical distancing essential for the control of the COVID-19 pandemic, WHO recommended postponement of all neglected tropical disease (NTD) control activities that involve community-based surveys, active case finding, and mass drug administration in April, 2020. Following revised guidance later in 2020, and after interruptions to NTD programmes of varying lengths, NTD programmes gradually restarted in the context of an ongoing pandemic. However, ongoing challenges and service gaps have been reported. This study aimed to evaluate the potential effect of the programmatic interruptions and strategies to mitigate this effect | ||
| 520 | |a METHODS: For seven NTDs, namely soil-transmitted helminths, schistosomiasis, lymphatic filariasis, onchocerciasis, trachoma, visceral leishmaniasis, and human African trypanosomiasis, we used mathematical transmission models to simulate the effect of programme interruptions on the dynamics of each of these diseases in different endemic settings. We also explored the potential benefit of implementing mitigation strategies, primarily in terms of minimising the delays to control targets | ||
| 520 | |a FINDINGS: We show that the effect of the COVID-19-induced interruption in terms of delay to achieving elimination goals might in some cases be much longer than the duration of the interruption. For schistosomiasis, onchocerciasis, trachoma, and visceral leishmaniasis, a mean delay of 2-3 years for a 1-year interruption is predicted in areas of highest prevalence. We also show that these delays can largely be mitigated by measures such as additional mass drug administration or enhanced case-finding | ||
| 520 | |a INTERPRETATION: The COVID-19 pandemic has brought infectious disease control to the forefront of global consciousness. It is essential that the NTDs, so long neglected in terms of research and financial support, are not overlooked, and remain a priority in health service planning and funding | ||
| 520 | |a FUNDING: Bill & Melinda Gates Foundation, Medical Research Council, and the UK Foreign, Commonwealth & Development Office | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 7 | |a Soil |2 NLM | |
| 700 | 1 | |a Le Rutte, Epke A |e verfasserin |4 aut | |
| 700 | 1 | |a Castaño, Soledad |e verfasserin |4 aut | |
| 700 | 1 | |a Blok, David J |e verfasserin |4 aut | |
| 700 | 1 | |a Toor, Jaspreet |e verfasserin |4 aut | |
| 700 | 1 | |a Giardina, Federica |e verfasserin |4 aut | |
| 700 | 1 | |a Davis, Emma L |e verfasserin |4 aut | |
| 700 | 0 | |a NTD Modelling Consortium |e verfasserin |4 aut | |
| 700 | 1 | |a Aliee, Maryam |e investigator |4 oth | |
| 700 | 1 | |a Anderson, Roy M |e investigator |4 oth | |
| 700 | 1 | |a Ayabina, Diepreye |e investigator |4 oth | |
| 700 | 1 | |a Basáñez, Maria-Gloria |e investigator |4 oth | |
| 700 | 1 | |a Blumberg, Seth |e investigator |4 oth | |
| 700 | 1 | |a Caja Rivera, Rocio M |e investigator |4 oth | |
| 700 | 1 | |a Chitnis, Nakul |e investigator |4 oth | |
| 700 | 1 | |a Coffeng, Luc E |e investigator |4 oth | |
| 700 | 1 | |a Davis, Christopher N |e investigator |4 oth | |
| 700 | 1 | |a Deiner, Michael |e investigator |4 oth | |
| 700 | 1 | |a Diggle, Peter J |e investigator |4 oth | |
| 700 | 1 | |a Fronterrè, Claudio |e investigator |4 oth | |
| 700 | 1 | |a Giorgi, Emanuele |e investigator |4 oth | |
| 700 | 1 | |a Graham, Matthew |e investigator |4 oth | |
| 700 | 1 | |a Hamley, Jonathan Id |e investigator |4 oth | |
| 700 | 1 | |a Hollingsworth, T Deirdre |e investigator |4 oth | |
| 700 | 1 | |a Keeling, Matt J |e investigator |4 oth | |
| 700 | 1 | |a Kura, Klodeta |e investigator |4 oth | |
| 700 | 1 | |a Lietman, Thomas M |e investigator |4 oth | |
| 700 | 1 | |a Malizia, Veronica |e investigator |4 oth | |
| 700 | 1 | |a Medley, Graham F |e investigator |4 oth | |
| 700 | 1 | |a Michael, Edwin |e investigator |4 oth | |
| 700 | 1 | |a Thumbi, S Mwangi |e investigator |4 oth | |
| 700 | 1 | |a Mutono, Nyamai |e investigator |4 oth | |
| 700 | 1 | |a Porco, Travis |e investigator |4 oth | |
| 700 | 1 | |a Prada, Joaquín M |e investigator |4 oth | |
| 700 | 1 | |a Rock, Kat S |e investigator |4 oth | |
| 700 | 1 | |a Sharma, Swarnali |e investigator |4 oth | |
| 700 | 1 | |a Spencer, Simon |e investigator |4 oth | |
| 700 | 1 | |a Stolk, Wilma A |e investigator |4 oth | |
| 700 | 1 | |a Touloupou, Panayiota |e investigator |4 oth | |
| 700 | 1 | |a Vasconcelos, Andreia |e investigator |4 oth | |
| 700 | 1 | |a Vegvari, Carolin |e investigator |4 oth | |
| 700 | 1 | |a de Vlas, Sake J |e investigator |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |t The Lancet. Global health |d 2013 |g 10(2022), 11 vom: 01. Nov., Seite e1600-e1611 |w (DE-627)NLM237515954 |x 2214-109X |7 nnns |
| 773 | 1 | 8 | |g volume:10 |g year:2022 |g number:11 |g day:01 |g month:11 |g pages:e1600-e1611 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/S2214-109X(22)00360-6 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 10 |j 2022 |e 11 |b 01 |c 11 |h e1600-e1611 | ||