Facile synthesis of 6-organyl-4-(trifluoromethyl)pyridin-2(1H)-ones and their polyfluoroalkyl-containing analogs
© Springer Science+Business Media LLC 2022..
The three-component cyclization of 3-polyfluoroalkyl-3-oxopropanoates and methyl ketones with ammonium acetate affords 6-organyl-4-(polyfluoroalkyl)pyridin-2(1H)-ones (organyl is alkyl, aryl, or hetaryl). The synthesized pyridones were evaluated for antifungal, antibacterial, and analgesic activity.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:71 |
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| Enthalten in: |
Russian chemical bulletin = Izvestiia Akademii nauk. Seriia khimicheskaia - 71(2022), 8 vom: 27., Seite 1687-1700 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Kushch, S O [VerfasserIn] |
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| Links: |
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| Themen: |
3-polyfluoroalkyl-3-oxopropanoates |
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| Anmerkungen: |
Date Revised 04.10.2022 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1007/s11172-022-3579-y |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM347009530 |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © Springer Science+Business Media LLC 2022. | ||
| 520 | |a The three-component cyclization of 3-polyfluoroalkyl-3-oxopropanoates and methyl ketones with ammonium acetate affords 6-organyl-4-(polyfluoroalkyl)pyridin-2(1H)-ones (organyl is alkyl, aryl, or hetaryl). The synthesized pyridones were evaluated for antifungal, antibacterial, and analgesic activity | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a 3-polyfluoroalkyl-3-oxopropanoates | |
| 650 | 4 | |a 4-(trifluoromethyl)pyridin-2-ones | |
| 650 | 4 | |a ammonium acetate | |
| 650 | 4 | |a ethyl trifluoroacetoacetate | |
| 650 | 4 | |a methyl ketones | |
| 650 | 4 | |a three-component reaction | |
| 700 | 1 | |a Goryaeva, M V |e verfasserin |4 aut | |
| 700 | 1 | |a Burgart, Ya V |e verfasserin |4 aut | |
| 700 | 1 | |a Triandafilova, G A |e verfasserin |4 aut | |
| 700 | 1 | |a Malysheva, K O |e verfasserin |4 aut | |
| 700 | 1 | |a Krasnykh, O P |e verfasserin |4 aut | |
| 700 | 1 | |a Gerasimova, N A |e verfasserin |4 aut | |
| 700 | 1 | |a Evstigneeva, N P |e verfasserin |4 aut | |
| 700 | 1 | |a Saloutin, V I |e verfasserin |4 aut | |
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