Primary adrenal insufficiency masking as an adrenal B-cell lymphoma

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We report here a woman in her 70s presenting with adrenal insufficiency secondary to a primary adrenal lymphoma. The patient had a previous history of aphthous ulcers on dexamethasone and was referred to endocrinology with symptoms of fatigue and orthostasis. Subsequent Cosyntropin stimulation showed primary adrenal insufficiency and adrenal CT demonstrated large infiltrative masses. Adrenal biopsy confirmed the diagnosis of primary adrenal lymphoma of the B-cell type. This case demonstrates the importance of including lymphoma in the differential diagnosis of adrenal insufficiency, particularly in the elderly population and in the setting of negative 21-hydroxlyase antibody results.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:15

Enthalten in:

BMJ case reports - 15(2022), 9 vom: 27. Sept.

Sprache:

Englisch

Beteiligte Personen:

Kuhn, Eric [VerfasserIn]
Sanchez, John R [VerfasserIn]
Shakir, Mohamed Km [VerfasserIn]
Hoang, Thanh Duc [VerfasserIn]

Links:

Volltext

Themen:

16960-16-0
7S5I7G3JQL
Adrenal disorders
Case Reports
Cosyntropin
Dexamethasone
Endocrine system
Haematology (drugs and medicines)
Haematology (incl blood transfusion)
Journal Article
Oncology

Anmerkungen:

Date Completed 29.09.2022

Date Revised 30.09.2022

published: Electronic

Citation Status MEDLINE

doi:

10.1136/bcr-2022-250973

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM346830443