Photothermal release of an encapsulated therapeutic agent from polymer-wrapped gold nanoparticles
This journal is © The Royal Society of Chemistry..
Visible light is used to generate heat from gold nanoparticles wrapped in an amphiphilic polymer shell and trigger a reverse Diels-Alder reaction of a 'caged' tyrphostin therapeutic agent. The hydrophilic nature of the released agent results in it travelling from the polymer to the bulk medium, while the byproduct of the reaction is trapped in the hydrophobic layer of the nano-assembly.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:3 |
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| Enthalten in: |
Nanoscale advances - 3(2021), 16 vom: 10. Aug., Seite 4669-4673 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Baker, Daina V [VerfasserIn] |
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| Links: |
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| Themen: |
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| Anmerkungen: |
Date Revised 24.09.2022 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1039/d1na00289a |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM346507227 |
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| 520 | |a Visible light is used to generate heat from gold nanoparticles wrapped in an amphiphilic polymer shell and trigger a reverse Diels-Alder reaction of a 'caged' tyrphostin therapeutic agent. The hydrophilic nature of the released agent results in it travelling from the polymer to the bulk medium, while the byproduct of the reaction is trapped in the hydrophobic layer of the nano-assembly | ||
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| 700 | 1 | |a Branda, Neil R |e verfasserin |4 aut | |
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