Associations between presence of diabetes, mortality and fracture type in individuals with a hip fracture
Copyright © 2022 The Author(s). Published by Elsevier B.V. All rights reserved..
AIMS: An overlooked aspect of diabetes is an increased risk of hip fractures, with associated mortality. We investigated whether fracture type and/or burden of comorbidities explains the increased risk of mortality in diabetes after hip fracture.
METHODS: For this cohort study, we used a de-identified data set of hip fracture patients registered in a quality-of-care registry (2017/2018) included in Maastricht University Medical Centre.
RESULTS: Among 594 hip fracture patients, 90 (15.2 %) had diabetes. Median (IQR) age was 82 (71-87) years and 63.8 % were women. Compared to patients without, patients with diabetes had higher median Charlson Comorbidity Index [1 (0-2) vs 0 (0-2), P < 0.001)] and were more likely to sustain intertrochanteric/subtrochanteric fractures [54.4 vs 38.7 %, P = 0.02]. Over a median follow-up of 2.7 (1.6-3.3) years, crude mortality rate was 30.8 % in patients without and 50.0 % in patients with diabetes. This association remained unaltered after adjustment for age, sex, BMI, fracture type or burden of co-morbidities.
CONCLUSION: Individuals with diabetes display a greatly increased absolute mortality risk after hip fracture. This association was not attenuated after adjustment for fracture type or non-diabetes associated co-morbidity. These findings have important implications for diabetes care in hip fracture patients, and underline the importance of fracture prevention.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2022 |
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Erschienen: |
2022 |
Enthalten in: |
Zur Gesamtaufnahme - volume:192 |
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Enthalten in: |
Diabetes research and clinical practice - 192(2022) vom: 10. Okt., Seite 110084 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Spaetgens, Bart [VerfasserIn] |
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Links: |
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Themen: |
Diabetes |
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Anmerkungen: |
Date Completed 01.11.2022 Date Revised 01.11.2022 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1016/j.diabres.2022.110084 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM346393671 |
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500 | |a published: Print-Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a Copyright © 2022 The Author(s). Published by Elsevier B.V. All rights reserved. | ||
520 | |a AIMS: An overlooked aspect of diabetes is an increased risk of hip fractures, with associated mortality. We investigated whether fracture type and/or burden of comorbidities explains the increased risk of mortality in diabetes after hip fracture | ||
520 | |a METHODS: For this cohort study, we used a de-identified data set of hip fracture patients registered in a quality-of-care registry (2017/2018) included in Maastricht University Medical Centre | ||
520 | |a RESULTS: Among 594 hip fracture patients, 90 (15.2 %) had diabetes. Median (IQR) age was 82 (71-87) years and 63.8 % were women. Compared to patients without, patients with diabetes had higher median Charlson Comorbidity Index [1 (0-2) vs 0 (0-2), P < 0.001)] and were more likely to sustain intertrochanteric/subtrochanteric fractures [54.4 vs 38.7 %, P = 0.02]. Over a median follow-up of 2.7 (1.6-3.3) years, crude mortality rate was 30.8 % in patients without and 50.0 % in patients with diabetes. This association remained unaltered after adjustment for age, sex, BMI, fracture type or burden of co-morbidities | ||
520 | |a CONCLUSION: Individuals with diabetes display a greatly increased absolute mortality risk after hip fracture. This association was not attenuated after adjustment for fracture type or non-diabetes associated co-morbidity. These findings have important implications for diabetes care in hip fracture patients, and underline the importance of fracture prevention | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Diabetes | |
650 | 4 | |a Hip fractures | |
650 | 4 | |a In-hospital complications | |
650 | 4 | |a Older individuals | |
700 | 1 | |a Brouns, Steffie H A |e verfasserin |4 aut | |
700 | 1 | |a Linkens, Aimée E M J H |e verfasserin |4 aut | |
700 | 1 | |a Poeze, Martijn |e verfasserin |4 aut | |
700 | 1 | |a Ten Broeke, René H M |e verfasserin |4 aut | |
700 | 1 | |a Brüggemann, Renée A G |e verfasserin |4 aut | |
700 | 1 | |a Sipers, Walther |e verfasserin |4 aut | |
700 | 1 | |a Henry, Ronald M A |e verfasserin |4 aut | |
700 | 1 | |a Hanssen, Nordin M J |e verfasserin |4 aut | |
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