Applying bio-impedance vector analysis (BIVA) to adjust ultrafiltration rate in critically ill patients on continuous renal replacement therapy : A randomized controlled trial

Copyright © 2022 Elsevier Inc. All rights reserved..

BACKGROUND: Bioimpedance vector analysis (BIVA) has been suggested as a valuable tool in assessing volume status in critically ill patients. However, its effectiveness in guiding fluid removal by continuous renal replacement therapy (CRRT) has not been evaluated.

METHODS: In this randomized controlled trial, 65 critically ill patients receiving CRRT were allocated on a 1:1 ratio to have UF prescribed and adjusted using BIVA fluid assessment in the intervention group (32 patients) or conventional clinical parameters (33 patients). The primary outcome was the lean body mass (LBM) water content at CRRT discontinuation, and the secondary outcomes included the mortality rate, urinary output, the duration of ventilation support, and ICU stay.

RESULTS: The study group was associated with a lower water content of LBM (80.7 ± 9.4 vs. 85.9 ± 10.4%; p < 0.05), and a higher mean UF-rate and urinary output (1.5 ± 0.8 vs. 1.2 ± 0.5 ml/kg/h and 0.9 ± 0.9 vs 0.5 ± 0.6 ml/kg/h, both: p < 0.05). The mortality rate, the length of ICU stay, and ventilation support duration were similar.

CONCLUSION: BIVA guided UF prescription may be associated with a lower rate of fluid overload. Larger studies are required to evaluate its impact on patients' outcomes.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:72

Enthalten in:

Journal of critical care - 72(2022) vom: 15. Dez., Seite 154146

Sprache:

Englisch

Beteiligte Personen:

Rashid Farokhi, Farin [VerfasserIn]
Kalateh, Effat [VerfasserIn]
Shafaghi, Shadi [VerfasserIn]
Schneider, Antoine Guillaume [VerfasserIn]
Mortazavi, Seyed Mehdi [VerfasserIn]
Jamaati, Hamidreza [VerfasserIn]
Hashemian, Seyed Mohammad Reza [VerfasserIn]

Links:

Volltext

Themen:

059QF0KO0R
AKI
BIVA
Bio-impedance
CRRT
Critical illness
Fluid overload
Journal Article
Randomized Controlled Trial
Ultrafiltration rate
Water

Anmerkungen:

Date Completed 29.11.2022

Date Revised 14.12.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.jcrc.2022.154146

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM346330084