Molecular Mechanisms and Key Processes in Interstitial, Hemorrhagic and Radiation Cystitis

Cystitis is a bladder disease with a high rate of prevalence in the world population. This report focuses on Interstitial Cystitis (IC), Hemorrhagic Cystitis (HC) and Chronic Radiation Cystitis. These pathologies have different etiologies, but they share common symptoms, for instance, pain, bleeding, and a contracted bladder. Overall, treatments are quite similar for abacterial cystitis, and include bladder epithelium protective or anti-inflammatory agents, alleviating pain and reducing bleeding. This review summarizes the mechanisms that the pathologies have in common, for instance, bladder dysfunction and inflammation. Conversely, some mechanisms have been described as present in only one pathology, such as neural regulation. Based on these specificities, we propose identifying a mechanism that could be common to all the above-mentioned pathologies.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:11

Enthalten in:

Biology - 11(2022), 7 vom: 28. Juni

Sprache:

Englisch

Beteiligte Personen:

Brossard, Clément [VerfasserIn]
Lefranc, Anne-Charlotte [VerfasserIn]
Pouliet, Anne-Laure [VerfasserIn]
Simon, Jean-Marc [VerfasserIn]
Benderitter, Marc [VerfasserIn]
Milliat, Fabien [VerfasserIn]
Chapel, Alain [VerfasserIn]

Links:

Volltext

Themen:

Bleeding
Cancer
Cystitis
Inflammation
Journal Article
Mechanism
Pelvic radiation disease
Radiation
Review

Anmerkungen:

Date Revised 17.09.2022

published: Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.3390/biology11070972

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM346181798