Stochastic SIR model predicts the evolution of COVID-19 epidemics from public health and wastewater data in small and medium-sized municipalities : A one year study

© 2022 The Author(s)..

The level of unpredictability of the COVID-19 pandemics poses a challenge to effectively model its dynamic evolution. In this study we incorporate the inherent stochasticity of the SARS-CoV-2 virus spread by reinterpreting the classical compartmental models of infectious diseases (SIR type) as chemical reaction systems modeled via the Chemical Master Equation and solved by Monte Carlo Methods. Our model predicts the evolution of the pandemics at the level of municipalities, incorporating for the first time (i) a variable infection rate to capture the effect of mitigation policies on the dynamic evolution of the pandemics (ii) SIR-with-jumps taking into account the possibility of multiple infections from a single infected person and (iii) data of viral load quantified by RT-qPCR from samples taken from Wastewater Treatment Plants. The model has been successfully employed for the prediction of the COVID-19 pandemics evolution in small and medium size municipalities of Galicia (Northwest of Spain).

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:164

Enthalten in:

Chaos, solitons, and fractals - 164(2022) vom: 05. Nov., Seite 112671

Sprache:

Englisch

Beteiligte Personen:

Pájaro, Manuel [VerfasserIn]
Fajar, Noelia M [VerfasserIn]
Alonso, Antonio A [VerfasserIn]
Otero-Muras, Irene [VerfasserIn]

Links:

Volltext

Themen:

COVID-19
Chemical master equation
Journal Article
SARS-coV-2
SIR model
Stochastic mechanistic model
Stochastic simulation algorithm

Anmerkungen:

Date Revised 21.12.2022

published: Print-Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.1016/j.chaos.2022.112671

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM346086094