Sociodemographic characterisation of antibiotic heavy users in the Danish elderly population

AIMS: The development of effective interventions to reduce inappropriate use of antibiotics in the elderly population requires knowledge on who can benefit from such interventions. Thus, we aimed to identify and characterise antibiotic heavy users among elderly patients in general practice with respect to sociodemographic variables.

METHODS: We conducted a retrospective nationwide register-based study on all Danish elderly citizens (⩾65 years) who redeemed an antibiotic prescription in 2017. Heavy users were defined as the 10% with the highest excess use, that is, their recorded use minus the average use for their sex, age group and comorbidity level as estimated from a linear regression model. Comparative analyses of sociodemographic characteristics (civil status, employment status, urbanity, educational level and country of origin) of heavy users and non-heavy users were performed using logistic regression models.

RESULTS: The study population consisted of 251,733 elderly individuals, who in total redeemed 573,265 prescriptions of antibiotics. Heavy users accounted for 68% of all excess use of antibiotics. In multivariable analyses, individuals with an educational level above basic schooling, non-retired, residing in an urban municipality and being born in a country outside Scandinavia all had lower odds of being a heavy user. Widowed, divorced or single individuals had higher odds of being a heavy user compared with married individuals. Relative importance analyses showed that civil status and educational level contributed considerably to the explained variance.

CONCLUSIONS: This study found an association between sociodemographic characteristics and risk of being a heavy user, indicating that sociodemographic variation exists with regard to antibiotic prescribing..

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:52

Enthalten in:

Scandinavian journal of public health - 52(2024), 1 vom: 29. Feb., Seite 31-38

Sprache:

Englisch

Beteiligte Personen:

Jensen, Maria L V [VerfasserIn]
Aabenhus, Rune M [VerfasserIn]
Holzknecht, Barbara J [VerfasserIn]
Bjerrum, Lars [VerfasserIn]
Siersma, Volkert [VerfasserIn]
COrdoba, Gloria [VerfasserIn]
Jensen, Jette N [VerfasserIn]

Links:

Volltext

Themen:

Aged
Aged 80 and over
Anti-Bacterial Agents
Antibacterial agents
Drug prescriptions
General practice
Journal Article
Sociodemographic factors

Anmerkungen:

Date Completed 06.02.2024

Date Revised 06.02.2024

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1177/14034948221119638

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM345934342