Current Cannabidiol Safety : A Review

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BACKGROUND: Marijuana, also known as cannabis, is the second most widely used illegal psychoactive substance smoked worldwide after tobacco, mainly due to the psychoactive effects induced by D-9-tetrahydrocannabinol (9-THC). Cannabidiol (CBD) is extracted from cannabis and may be used as an anti-inflammatory agent. Some patents on cannabidiol are discussed in this review. The cannabinoid is a non-psychoactive isomer of the more infamous tetrahydrocannabinol (THC); and is available in several administration modes, most known as CBD oil.

OBJECTIVES: This study aims to provide an enhanced review of cannabidiol properties used in treating inflammation. This review also emphasises the current safety profile of cannabidiol.

METHODS: Cannabis is also called Marijuana. It is the second most commonly used illegal psychoactive substance in the universe after tobacco. D-9-tetrahydrocannabinol (9-THC) present in cannabis produces psychoactive effects. Cannabidiol (CBD) extracted from cannabis is used for antiinflammatory purposes. Cannabis smoking causes various types of cancer, such as lung, tongue, and jaw. The current review took literature from Google Scholar, PubMed, and Google Patents. Many clinical investigations are included in this review.

RESULT: After analysing the literature on cannabis, it has been suggested that although cannabis is banned in some countries, it may be included in the treatment and mitigation of some diseases and symptoms like pain management, epilepsy, cancer, and anxiety disorder. Mild side effects were frequently observed in cannabis medications, which included infertility in females, liver damage, etc. Conclusion: Cannabis contains chemical compounds such as the cannabinoids delta-9- tetrahydrocannabinol (THC), a psychoactive substance, and non-psychoactive cannabidiol (CBD). Cannabidiol has been confirmed as an efficient treatment of epilepsy in several clinical trials, with one pure CBD product named Epidiolex. It is also used in treating anxiety and acne, as a pain reliever, and has anti-inflammatory properties.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:18

Enthalten in:

Current drug safety - 18(2023), 4 vom: 16., Seite 465-473

Sprache:

Englisch

Beteiligte Personen:

Singh, Chander [VerfasserIn]
Rao, Komal [VerfasserIn]
Yadav, Nikita [VerfasserIn]
Vashist, Yogesh [VerfasserIn]
Chugh, Palak [VerfasserIn]
Bansal, Nidhi [VerfasserIn]
Minocha, Neha [VerfasserIn]

Links:

Volltext

Themen:

19GBJ60SN5
7J8897W37S
Anti-Inflammatory Agents
CBD
Cannabidiol
Cannabinoids
Cannabis
D-9-tetrahydrocannabinol (9-THC)
Dronabinol
Journal Article
Marijuana
Review
Safety

Anmerkungen:

Date Completed 01.06.2023

Date Revised 07.03.2024

published: Print

Citation Status MEDLINE

doi:

10.2174/1574886317666220902100511

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM345740718