Obesity, CKD and gender on the 30-day in-hospital mortality risk in adults with COVID-19
© 2022 Revista Médica del Instituto Mexicano del Seguro Social..
Background: The coronavirus disease 2019 (COVID-19) pandemic is a serious health problem. The Mexican adult population has a high prevalence of obesity and chronic diseases that increase the risk of dying from this disease.
Objective: To identify comorbidities predicting the risk of mortality at 30 days in hospitalized adult subjects with positive laboratory COVID-19 test and to evaluate the interaction between chronic diseases and gender.
Material and methods: A retrospective cohort study was conducted in 2020, in a western region of the Mexican Pacific. Data from 51,135 hospitalized patients with positive COVID-19 test were analyzed and were retrieved from a normative system for the epidemiological surveillance of viral respiratory diseases (SINOLAVE, according to its initials in Spanish). Death within the first 30 days from hospital admission was the main outcome and risk ratios (RR) with 95% confidence intervals (95% CI) were calculated.
Results: The overall mortality rate was 49.6% and most of the comorbidities analyzed were associated with a higher risk of death. There were significant interactions between gender and obesity (p = 0.003) and chronic kidney disease (p = 0.019). The effect of obesity on the risk of a fatal outcome varied by gender: female, RR = 1.04 (95% CI 1.03-1.07); male, RR = 1.07 (95% CI: 1.06-1.09).
Conclusions: A high mortality was observed among the hospitalized patients analyzed and statistically significant factors associated with their risk were identified (gender, obesity, and kidney disease).
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:60 |
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| Enthalten in: |
Revista medica del Instituto Mexicano del Seguro Social - 60(2022), 5 vom: 31. Aug., Seite 540-547 |
| Sprache: |
Spanisch |
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| Weiterer Titel: |
Obesidad, ERC y género en el riesgo de mortalidad hospitalaria a 30 días en adultos con COVID-19 |
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| Beteiligte Personen: |
Murillo-Zamora, Efrén [VerfasserIn] |
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| Themen: |
COVID-19 |
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| Anmerkungen: |
Date Completed 07.09.2022 Date Revised 05.08.2023 published: Electronic Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| 245 | 1 | 0 | |a Obesity, CKD and gender on the 30-day in-hospital mortality risk in adults with COVID-19 |
| 246 | 3 | 3 | |a Obesidad, ERC y género en el riesgo de mortalidad hospitalaria a 30 días en adultos con COVID-19 |
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| 500 | |a Date Completed 07.09.2022 | ||
| 500 | |a Date Revised 05.08.2023 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2022 Revista Médica del Instituto Mexicano del Seguro Social. | ||
| 520 | |a Background: The coronavirus disease 2019 (COVID-19) pandemic is a serious health problem. The Mexican adult population has a high prevalence of obesity and chronic diseases that increase the risk of dying from this disease | ||
| 520 | |a Objective: To identify comorbidities predicting the risk of mortality at 30 days in hospitalized adult subjects with positive laboratory COVID-19 test and to evaluate the interaction between chronic diseases and gender | ||
| 520 | |a Material and methods: A retrospective cohort study was conducted in 2020, in a western region of the Mexican Pacific. Data from 51,135 hospitalized patients with positive COVID-19 test were analyzed and were retrieved from a normative system for the epidemiological surveillance of viral respiratory diseases (SINOLAVE, according to its initials in Spanish). Death within the first 30 days from hospital admission was the main outcome and risk ratios (RR) with 95% confidence intervals (95% CI) were calculated | ||
| 520 | |a Results: The overall mortality rate was 49.6% and most of the comorbidities analyzed were associated with a higher risk of death. There were significant interactions between gender and obesity (p = 0.003) and chronic kidney disease (p = 0.019). The effect of obesity on the risk of a fatal outcome varied by gender: female, RR = 1.04 (95% CI 1.03-1.07); male, RR = 1.07 (95% CI: 1.06-1.09) | ||
| 520 | |a Conclusions: A high mortality was observed among the hospitalized patients analyzed and statistically significant factors associated with their risk were identified (gender, obesity, and kidney disease) | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a Hospital Mortality | |
| 650 | 4 | |a Inpatients | |
| 650 | 4 | |a Obesity | |
| 650 | 4 | |a Renal Insufficiency, Chronic | |
| 700 | 1 | |a Hernández-Suárez, Carlos M |e verfasserin |4 aut | |
| 700 | 1 | |a Guzmán-Esquive, José |e verfasserin |4 aut | |
| 700 | 1 | |a Delgado-Enciso, Iván |e verfasserin |4 aut | |
| 700 | 1 | |a Guzmán-Solórzano, José Alejandro |e verfasserin |4 aut | |
| 700 | 1 | |a Ochoa-Castro, María R |e verfasserin |4 aut | |
| 700 | 1 | |a García-García, Hossana |e verfasserin |4 aut | |
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