Is self-rated health associated with cardiovascular risk factors and disease in a low-income setting? A cross-sectional study from the Amazon Basin of Brazil
© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ..
OBJECTIVE: Prior studies have suggested that self-rated health may be a useful indicator of cardiovascular disease. Consequently, we aimed to assess the relationship between self-rated health, cardiovascular risk factors and subclinical cardiac disease in the Amazon Basin.
DESIGN: Cross-sectional study.
SETTING, PARTICIPANTS AND INTERVENTIONS: In participants from the Amazon Basin of Brazil we obtained self-rated health according to a Visual Analogue Scale, ranging from 0 (poor) to 100 (excellent). We performed questionnaires, physical examination and echocardiography. Logistic and linear regression models were applied to assess self-rated health, cardiac risk factors and cardiac disease by echocardiography. Multivariable models were mutually adjusted for other cardiovascular risk factors, clinical and socioeconomic data, and known cardiac disease.
OUTCOME MEASURES: Cardiovascular risk factors and subclincial cardiac disease by echocardiography.
RESULTS: A total of 574 participants (mean age 41 years, 61% female) provided information on self-rated health (mean 75±21 (IQR 60-90) points). Self-rated health (per 10-point increase) was negatively associated with hypertension (OR 0.87 (95% CI 0.78 to 0.97), p=0.01), hypercholesterolaemia (OR 0.89 (95%CI 0.80 to 0.99), p=0.04) and positively with healthy diet (OR 1.13 (95%CI 1.04 to 1.24), p=0.004). Sex modified these associations (p-interaction <0.05) such that higher self-rated health was associated with healthy diet and physical activity in men, and lower odds of hypertension and hypercholesterolaemia in women. No relationship was found with left ventricular ejection fraction <45% (OR 0.97 (95% CI 0.77 to 1.23), p=0.8), left ventricular hypertrophy (OR 0.97 (95% CI 0.76 to 1.24), p=0.81) or diastolic dysfunction (OR 1.09 (95% CI 0.85 to 1.40), p=0.51).
CONCLUSION: Self-rated health was positively associated with health parameters in the Amazon Basin, but not with subclinical cardiac disease by echocardiography. Our findings are of hypothesis generating nature and future studies should aim to determine whether assessment of self-rated health may be useful for screening related to policy-making or lifestyle interventions.
TRIAL REGISTRATION NUMBER: Clinicaltrials.gov: NCT04445103; Post-results.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
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| Enthalten in: |
BMJ open - 12(2022), 8 vom: 30. Aug., Seite e058277 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Holm, Anna Engell [VerfasserIn] |
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| Links: |
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| Themen: |
CARDIOLOGY |
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| Anmerkungen: |
Date Completed 02.09.2022 Date Revised 15.09.2022 published: Electronic ClinicalTrials.gov: NCT04445103 Citation Status MEDLINE |
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| doi: |
10.1136/bmjopen-2021-058277 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM345591259 |
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| 100 | 1 | |a Holm, Anna Engell |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Is self-rated health associated with cardiovascular risk factors and disease in a low-income setting? A cross-sectional study from the Amazon Basin of Brazil |
| 264 | 1 | |c 2022 | |
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| 500 | |a Date Completed 02.09.2022 | ||
| 500 | |a Date Revised 15.09.2022 | ||
| 500 | |a published: Electronic | ||
| 500 | |a ClinicalTrials.gov: NCT04445103 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. | ||
| 520 | |a OBJECTIVE: Prior studies have suggested that self-rated health may be a useful indicator of cardiovascular disease. Consequently, we aimed to assess the relationship between self-rated health, cardiovascular risk factors and subclinical cardiac disease in the Amazon Basin | ||
| 520 | |a DESIGN: Cross-sectional study | ||
| 520 | |a SETTING, PARTICIPANTS AND INTERVENTIONS: In participants from the Amazon Basin of Brazil we obtained self-rated health according to a Visual Analogue Scale, ranging from 0 (poor) to 100 (excellent). We performed questionnaires, physical examination and echocardiography. Logistic and linear regression models were applied to assess self-rated health, cardiac risk factors and cardiac disease by echocardiography. Multivariable models were mutually adjusted for other cardiovascular risk factors, clinical and socioeconomic data, and known cardiac disease | ||
| 520 | |a OUTCOME MEASURES: Cardiovascular risk factors and subclincial cardiac disease by echocardiography | ||
| 520 | |a RESULTS: A total of 574 participants (mean age 41 years, 61% female) provided information on self-rated health (mean 75±21 (IQR 60-90) points). Self-rated health (per 10-point increase) was negatively associated with hypertension (OR 0.87 (95% CI 0.78 to 0.97), p=0.01), hypercholesterolaemia (OR 0.89 (95%CI 0.80 to 0.99), p=0.04) and positively with healthy diet (OR 1.13 (95%CI 1.04 to 1.24), p=0.004). Sex modified these associations (p-interaction <0.05) such that higher self-rated health was associated with healthy diet and physical activity in men, and lower odds of hypertension and hypercholesterolaemia in women. No relationship was found with left ventricular ejection fraction <45% (OR 0.97 (95% CI 0.77 to 1.23), p=0.8), left ventricular hypertrophy (OR 0.97 (95% CI 0.76 to 1.24), p=0.81) or diastolic dysfunction (OR 1.09 (95% CI 0.85 to 1.40), p=0.51) | ||
| 520 | |a CONCLUSION: Self-rated health was positively associated with health parameters in the Amazon Basin, but not with subclinical cardiac disease by echocardiography. Our findings are of hypothesis generating nature and future studies should aim to determine whether assessment of self-rated health may be useful for screening related to policy-making or lifestyle interventions | ||
| 520 | |a TRIAL REGISTRATION NUMBER: Clinicaltrials.gov: NCT04445103; Post-results | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a CARDIOLOGY | |
| 650 | 4 | |a MENTAL HEALTH | |
| 650 | 4 | |a PUBLIC HEALTH | |
| 700 | 1 | |a Gomes, Laura Cordeiro |e verfasserin |4 aut | |
| 700 | 1 | |a Wegener, Alma |e verfasserin |4 aut | |
| 700 | 1 | |a Lima, Karine O |e verfasserin |4 aut | |
| 700 | 1 | |a Matos, Luan O |e verfasserin |4 aut | |
| 700 | 1 | |a Vieira, Isabelle V M |e verfasserin |4 aut | |
| 700 | 1 | |a Kaagaard, Molly D |e verfasserin |4 aut | |
| 700 | 1 | |a Pareek, Manan |e verfasserin |4 aut | |
| 700 | 1 | |a de Souza, Rodrigo Medeiros |e verfasserin |4 aut | |
| 700 | 1 | |a Marinho, Claudio Romero Farias |e verfasserin |4 aut | |
| 700 | 1 | |a Biering-Sørensen, Tor |e verfasserin |4 aut | |
| 700 | 1 | |a Silvestre, Odilson M |e verfasserin |4 aut | |
| 700 | 1 | |a Brainin, Philip |e verfasserin |4 aut | |
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