Production of medium-sized chitosan oligomers using molecular sieves and their antibacterial activity

Copyright © 2022 Elsevier Ltd. All rights reserved..

Chitosan, derived from the natural polysaccharide chitin, was fragmented in very dilute acetic acid solutions using zeolites and molecular sieves, a type of zeolites, under variable reaction conditions of temperature, acid concentration, duration of reaction, and zeolites of variable pore sizes. Fragmentation resulted in the formation of appreciable amounts of chitosan oligomers comprised of 4-8 units, which were studied by using LC-MS, MS, as well as IR spectroscopy. The prepared fragments were tested for their biological activity and some of them showed antibacterial activity against Gram-positive bacteria.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:295

Enthalten in:

Carbohydrate polymers - 295(2022) vom: 01. Nov., Seite 119889

Sprache:

Englisch

Beteiligte Personen:

Abu-Sbeih, Khaleel A [VerfasserIn]
Al-Mazaideh, Ghassab M [VerfasserIn]
Al-Zereini, Wael A [VerfasserIn]

Links:

Volltext

Themen:

1318-02-1
1398-61-4
9012-76-4
Anti-Bacterial Agents
Antibacterial
Chitin
Chitosan
Chitosan fragmentation
Chitosan oligomers
IR spectroscopy
Journal Article
LC-MS
Molecular sieves
Zeolites

Anmerkungen:

Date Completed 23.08.2022

Date Revised 23.08.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.carbpol.2022.119889

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM345075536