Enhancing respiratory disease diagnosis by bronchoalveolar lavage in Kashmir : an audit of findings
© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ..
OBJECTIVE: To study bronchoalveolar lavage (BAL) findings in various respiratory diseases in children in Kashmir India.
DESIGN: Prospective observational study.
SETTING: Paediatric department of the tertiary care hospital.
PATIENTS: Children of both genders from 1 month to 17 years of age INTERVENTION: All studied patients underwent flexible bronchoscopy and BAL.
OUTCOME MEASURE: To observe the BAL findings in various respiratory diseases in the studied population.
RESULTS: A total of 283 patients underwent BAL procedure. The positive BAL report was received in 131 (46%) patients. Out of these, 55 (42%) patients had positive BAL culture/ microscopy for different bacterial (50) and fungal species (Candida spp (3), Mucormycosis (1) and Aspergillus (1)). MTB was isolated in 25 (19%) patients. Twenty-three (17.5%) patients had bronchoalveolar lavage fluid (BALF) positive for pulmonary hydatidosis. Foamy macrophages were seen in 13 patients, significant eosinophilia in nine patients and hemosiderin-laden macrophages were seen in three patients.
CONCLUSION: We found BALF a very useful sample for the evaluation of many infective and non-infective respiratory diseases in our region, which otherwise lacks high end diagnostics. 46% of our patients had some abnormalities in the BAL specimen. It provided us with valuable information regarding organism profile and drug sensitivity in case of lung infection. BALF analysis was also found useful in the diagnosis of some non-infective pulmonary disorders like acute eosinophilic pneumonia, aspiration syndromes and bronchial asthma.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:107 |
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| Enthalten in: |
Archives of disease in childhood - 107(2022), 12 vom: 01. Dez., Seite 1079-1082 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Bhat, Javeed Iqbal [VerfasserIn] |
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| Links: |
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| Themen: |
Journal Article |
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| Anmerkungen: |
Date Completed 21.11.2022 Date Revised 12.12.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1136/archdischild-2022-323823 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM344677664 |
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| 245 | 1 | 0 | |a Enhancing respiratory disease diagnosis by bronchoalveolar lavage in Kashmir |b an audit of findings |
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| 500 | |a Date Completed 21.11.2022 | ||
| 500 | |a Date Revised 12.12.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ. | ||
| 520 | |a OBJECTIVE: To study bronchoalveolar lavage (BAL) findings in various respiratory diseases in children in Kashmir India | ||
| 520 | |a DESIGN: Prospective observational study | ||
| 520 | |a SETTING: Paediatric department of the tertiary care hospital | ||
| 520 | |a PATIENTS: Children of both genders from 1 month to 17 years of age INTERVENTION: All studied patients underwent flexible bronchoscopy and BAL | ||
| 520 | |a OUTCOME MEASURE: To observe the BAL findings in various respiratory diseases in the studied population | ||
| 520 | |a RESULTS: A total of 283 patients underwent BAL procedure. The positive BAL report was received in 131 (46%) patients. Out of these, 55 (42%) patients had positive BAL culture/ microscopy for different bacterial (50) and fungal species (Candida spp (3), Mucormycosis (1) and Aspergillus (1)). MTB was isolated in 25 (19%) patients. Twenty-three (17.5%) patients had bronchoalveolar lavage fluid (BALF) positive for pulmonary hydatidosis. Foamy macrophages were seen in 13 patients, significant eosinophilia in nine patients and hemosiderin-laden macrophages were seen in three patients | ||
| 520 | |a CONCLUSION: We found BALF a very useful sample for the evaluation of many infective and non-infective respiratory diseases in our region, which otherwise lacks high end diagnostics. 46% of our patients had some abnormalities in the BAL specimen. It provided us with valuable information regarding organism profile and drug sensitivity in case of lung infection. BALF analysis was also found useful in the diagnosis of some non-infective pulmonary disorders like acute eosinophilic pneumonia, aspiration syndromes and bronchial asthma | ||
| 650 | 4 | |a Observational Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Microbiology | |
| 650 | 4 | |a Respiratory Medicine | |
| 700 | 1 | |a Tramboo, Zubair M |e verfasserin |4 aut | |
| 700 | 1 | |a Shah, Tajamul Hussain |e verfasserin |4 aut | |
| 700 | 1 | |a Charoo, Bashir Ahmad |e verfasserin |4 aut | |
| 700 | 1 | |a Qazi, Iqbal Ahmad |e verfasserin |4 aut | |
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