Platelet-Rich Plasma in the Treatment of Facet Mediated Low Back Pain : A Comprehensive Review
Background: Facet-mediated pain is a major cause of low back pain and as a result, is a significant cause of morbidity, including disability and reduced functionality.
Setting: The present investigation involved a PubMed literature review between June 1, and 2021-January 1, 2022.
Methods: We systematically reviewed was carried Pubmed using the search terms "platelet-rich plasma", "inflammatory mediators", "facet arthropathy", "axial back pain", and "leukoreduction". Data extraction and quality assessment were performed by 3 independent reviewers. Out of the studies analyzed 2 were retrospective, while 1 was a prospective study.
Results: PRP injections for facet mediated or modulated pain are an alternative to conventional pharmacotherapies and interventional injections/radiofrequency. There are limited numbers of studies in world literature at present.
Limitations: Small number of articles in the world literature and small numbers of patients in those published studies.
Conclusions: At present, there are limited studies in the literature; however, larger well-designed studies are warranted to precisely understand efficacy, potential side effects and best practice techniques for PRP injections for facet mediated or modulated pain.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:14 |
|---|---|
| Enthalten in: |
Orthopedic reviews - 14(2022), 4 vom: 26., Seite 37076 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Patel, Aakash [VerfasserIn] |
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| Links: |
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| Themen: |
Chronic pain |
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| Anmerkungen: |
Date Revised 22.11.2022 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.52965/001c.37076 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM344302385 |
|---|
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| 520 | |a Background: Facet-mediated pain is a major cause of low back pain and as a result, is a significant cause of morbidity, including disability and reduced functionality | ||
| 520 | |a Setting: The present investigation involved a PubMed literature review between June 1, and 2021-January 1, 2022 | ||
| 520 | |a Methods: We systematically reviewed was carried Pubmed using the search terms "platelet-rich plasma", "inflammatory mediators", "facet arthropathy", "axial back pain", and "leukoreduction". Data extraction and quality assessment were performed by 3 independent reviewers. Out of the studies analyzed 2 were retrospective, while 1 was a prospective study | ||
| 520 | |a Results: PRP injections for facet mediated or modulated pain are an alternative to conventional pharmacotherapies and interventional injections/radiofrequency. There are limited numbers of studies in world literature at present | ||
| 520 | |a Limitations: Small number of articles in the world literature and small numbers of patients in those published studies | ||
| 520 | |a Conclusions: At present, there are limited studies in the literature; however, larger well-designed studies are warranted to precisely understand efficacy, potential side effects and best practice techniques for PRP injections for facet mediated or modulated pain | ||
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| 650 | 4 | |a platelet rich plasma | |
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| 700 | 1 | |a Varrassi, Giustino |e verfasserin |4 aut | |
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