The early outcomes of complex abdominal wall reconstruction with polyvinylidene (PVDF) mesh in the setting of active infection : a prospective series
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature..
PURPOSE: The use of synthetic mesh to repair infected abdominal wall defects remains controversial. Polyvinylidene fluoride (PVDF) mesh was introduced in 2002 as an alternative to polypropylene, with the advantages of improved biostability, lowered bending stiffness, and minimum tissue response. This study aimed to evaluate the short-term outcomes of using PVDF mesh to treat infected abdominal wall defects in the elective setting.
METHODS: This prospective clinical trial started in 2016 and was designed to evaluate the short- and mid-term outcomes of 38 patients submitted to abdominal wall reconstruction in the setting of active mesh infection and/or enteric fistulas (AI) when compared to a group of 38 patients submitted to clean ventral hernia repairs (CC). Patients were submitted to single-staged repairs, using onlay PVDF mesh (DynaMesh®-CICAT) reinforcement to treat their defects.
RESULTS: Groups had comparable demographic characteristics. The AI group had more previous abdominal operations and required a longer operative and anesthesia time. At 30 days, surgical site occurrences were observed in 16 (42.1%) AI vs. 17 (44.7%) CC, p = 0.817; surgical site infection occurred in 4 (10.5%) AI vs. 6 (15.8%) CC, p = 0.497; and a higher number of procedural interventions were required in the CC group, 15.8 AI vs. 28.9% CC, p = 0.169. Both groups did not have chronic infections at 1 year of follow-up, and one hernia recurrence was observed in the AI group.
CONCLUSIONS: The use of PVDF mesh in the infected setting presented favorable results with a low incidence of wound infection.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:407 |
|---|---|
| Enthalten in: |
Langenbeck's archives of surgery - 407(2022), 7 vom: 29. Nov., Seite 3089-3099 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Birolini, Claudio [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
24937-79-9 |
|---|
| Anmerkungen: |
Date Completed 09.11.2022 Date Revised 09.11.2022 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1007/s00423-022-02625-2 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM344260038 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM344260038 | ||
| 003 | DE-627 | ||
| 005 | 20231226022342.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00423-022-02625-2 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1147.xml |
| 035 | |a (DE-627)NLM344260038 | ||
| 035 | |a (NLM)35906299 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Birolini, Claudio |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The early outcomes of complex abdominal wall reconstruction with polyvinylidene (PVDF) mesh in the setting of active infection |b a prospective series |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 09.11.2022 | ||
| 500 | |a Date Revised 09.11.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. | ||
| 520 | |a PURPOSE: The use of synthetic mesh to repair infected abdominal wall defects remains controversial. Polyvinylidene fluoride (PVDF) mesh was introduced in 2002 as an alternative to polypropylene, with the advantages of improved biostability, lowered bending stiffness, and minimum tissue response. This study aimed to evaluate the short-term outcomes of using PVDF mesh to treat infected abdominal wall defects in the elective setting | ||
| 520 | |a METHODS: This prospective clinical trial started in 2016 and was designed to evaluate the short- and mid-term outcomes of 38 patients submitted to abdominal wall reconstruction in the setting of active mesh infection and/or enteric fistulas (AI) when compared to a group of 38 patients submitted to clean ventral hernia repairs (CC). Patients were submitted to single-staged repairs, using onlay PVDF mesh (DynaMesh®-CICAT) reinforcement to treat their defects | ||
| 520 | |a RESULTS: Groups had comparable demographic characteristics. The AI group had more previous abdominal operations and required a longer operative and anesthesia time. At 30 days, surgical site occurrences were observed in 16 (42.1%) AI vs. 17 (44.7%) CC, p = 0.817; surgical site infection occurred in 4 (10.5%) AI vs. 6 (15.8%) CC, p = 0.497; and a higher number of procedural interventions were required in the CC group, 15.8 AI vs. 28.9% CC, p = 0.169. Both groups did not have chronic infections at 1 year of follow-up, and one hernia recurrence was observed in the AI group | ||
| 520 | |a CONCLUSIONS: The use of PVDF mesh in the infected setting presented favorable results with a low incidence of wound infection | ||
| 650 | 4 | |a Clinical Trial | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a CICAT mesh | |
| 650 | 4 | |a DynaMesh® | |
| 650 | 4 | |a Enteric fistula | |
| 650 | 4 | |a Incisional hernia | |
| 650 | 4 | |a Mesh infection | |
| 650 | 4 | |a Polyvinylidene mesh | |
| 650 | 4 | |a Ventral hernia | |
| 650 | 7 | |a polyvinylidene fluoride |2 NLM | |
| 650 | 7 | |a 24937-79-9 |2 NLM | |
| 700 | 1 | |a Tanaka, Eduardo Yassushi |e verfasserin |4 aut | |
| 700 | 1 | |a de Miranda, Jocielle Santos |e verfasserin |4 aut | |
| 700 | 1 | |a Murakami, Abel Hiroshi |e verfasserin |4 aut | |
| 700 | 1 | |a Damous, Sergio Henrique Bastos |e verfasserin |4 aut | |
| 700 | 1 | |a Utiyama, Edivaldo Massazo |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Langenbeck's archives of surgery |d 1998 |g 407(2022), 7 vom: 29. Nov., Seite 3089-3099 |w (DE-627)NLM095673148 |x 1435-2451 |7 nnns |
| 773 | 1 | 8 | |g volume:407 |g year:2022 |g number:7 |g day:29 |g month:11 |g pages:3089-3099 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s00423-022-02625-2 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 407 |j 2022 |e 7 |b 29 |c 11 |h 3089-3099 | ||