Case Report : Chemoradiation with Paclitaxel and Carboplatin Unveiling Leprosy Type 1 Downgrading Reaction
Type 1 lepra reaction (T1R) is a major complication seen in nonpolar forms of leprosy and leads to significant morbidity. The classification of T1R as up and downgrading, based on previously defined histopathological criteria (by Ridley), has therapeutic and prognostic implications. The trigger factors for these reactions are poorly described, especially in case of downgrading T1R and we describe a case of leprosy reaction that was possibly triggered by chemoradiation and elucidate the possible mechanism.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:107 |
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| Enthalten in: |
The American journal of tropical medicine and hygiene - 107(2022), 1 vom: 13. Juli, Seite 94-96 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Savitha, B [VerfasserIn] |
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| Links: |
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| Themen: |
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| Anmerkungen: |
Date Completed 29.07.2022 Date Revised 03.07.2023 published: Electronic-Print Citation Status MEDLINE |
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| doi: |
10.4269/ajtmh.22-0099 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM344151344 |
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| 520 | |a Type 1 lepra reaction (T1R) is a major complication seen in nonpolar forms of leprosy and leads to significant morbidity. The classification of T1R as up and downgrading, based on previously defined histopathological criteria (by Ridley), has therapeutic and prognostic implications. The trigger factors for these reactions are poorly described, especially in case of downgrading T1R and we describe a case of leprosy reaction that was possibly triggered by chemoradiation and elucidate the possible mechanism | ||
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| 700 | 1 | |a Sachdeva, Soumya |e verfasserin |4 aut | |
| 700 | 1 | |a Ahuja, Arvind |e verfasserin |4 aut | |
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