Nano-vaccination Strategies : Applications and Challenges for Intranasal Immunization

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The nasal route, a subgroup of mucosal delivery systems, constitutes a lucrative and encouraging substitute for administering drugs and vaccines. Over the years, a lot of research has been done in this area, and scientists have successfully explored this pathway using novel formulations to combat several infections. This review article aims to address the pathways of mucosal immunization, the dominance of the nasal route over other mucosal routes for immunization, and the mechanism of generation of immunogenic response via nasal route and nanotechnology-based approaches for intranasal vaccination. The immunotherapeutic and vaccinations for intranasal administration available in the market are also discussed, along with a brief overview of the products in the pipeline. It can also be assumed that such an approach can prove to be favorable in designing vaccinations for the current uncertain times. In spite of some dubious views on this.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:24

Enthalten in:

Current pharmaceutical biotechnology - 24(2023), 8 vom: 26., Seite 946-969

Sprache:

Englisch

Beteiligte Personen:

Pandya, Tosha [VerfasserIn]
Joshi, Prachi [VerfasserIn]
Pathak, Rudree [VerfasserIn]
Shah, Shreeraj [VerfasserIn]

Links:

Volltext

Themen:

COVID-19
Immunization
Intranasal
Journal Article
Mucosal
Nanotechnology
Review
Vaccination
Vaccines

Anmerkungen:

Date Completed 01.06.2023

Date Revised 01.06.2023

published: Print

Citation Status MEDLINE

doi:

10.2174/1389201023666220727105901

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM344142507