Clinical-epidemiologic variation in patients treated in the first and second wave of COVID-19 in Lambayeque, Peru : A cluster analysis

Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved..

OBJECTIVES: To identify differences in the clinical and epidemiologic characteristics of patients during the first and second waves of the COVID-19 pandemic at the EsSalud Lambayeque health care network, Peru.

METHODS: An analytical cross-sectional study of 53,912 patients enrolled during the first and second waves of COVID-19 was conducted. Cluster analysis based on clustering large applications (CLARA) was applied to clinical-epidemiologic data presented at the time of care. The two pandemic waves were compared using clinical-epidemiologic data from epidemiologic surveillance.

RESULTS: Cluster analysis identified four COVID-19 groups with a characteristic pattern. Cluster 1 included the largest number of participants in both waves, and the participants were predominantly female. Cluster 2 included patients with gastrointestinal, respiratory, and systemic symptoms. Cluster 3 was the "severe" cluster, characterized by older adults and patients with dyspnea or comorbidities (cardiovascular, diabetes, obesity). Cluster 4 included asymptomatic, pregnant, and less severe patients. We found differences in all clinical-epidemiologic characteristics according to the cluster to which they belonged.

CONCLUSION: Using cluster analysis, we identified characteristic patterns in each group. Respiratory, gastrointestinal, dyspnea, anosmia, and ageusia symptoms were higher in the second COVID-19 wave than the first COVID-19 wave.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:123

Enthalten in:

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 123(2022) vom: 01. Okt., Seite 212-220

Sprache:

Englisch

Beteiligte Personen:

Valladares-Garrido, Mario J [VerfasserIn]
Failoc-Rojas, Virgilio E [VerfasserIn]
Soto-Becerra, Percy [VerfasserIn]
Zeña-Ñañez, Sandra [VerfasserIn]
Torres-Roman, J Smith [VerfasserIn]
Fernández-Mogollón, Jorge L [VerfasserIn]
Colchado-Palacios, Irina G [VerfasserIn]
Apolaya-Segura, Carlos E [VerfasserIn]
Dávila-Gonzales, Jhoni A [VerfasserIn]
Arce-Villalobos, Laura R [VerfasserIn]
Neciosup-Puican, Roxana Del Pilar [VerfasserIn]
Calvay-Requejo, Alexander G [VerfasserIn]
Maguiña, Jorge L [VerfasserIn]
Apolaya-Segura, Moisés [VerfasserIn]
Díaz-Vélez, Cristian [VerfasserIn]

Links:

Volltext

Themen:

COVID-19
Cluster analysis
Coronavirus infection
Journal Article
Pandemic wave
Peru
Symptoms

Anmerkungen:

Date Completed 04.10.2022

Date Revised 17.12.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.ijid.2022.07.045

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM343919966