Clinical validity of the intraoperative histology in the diagnosis of prosthetic joint infection
Copyright © 2022 SECOT. Publicado por Elsevier España, S.L.U. All rights reserved..
BACKGROUND AND AIM: Different authors have demonstrated the usefulness of the histological analysis in the diagnosis of prosthetic joint infection; however, its clinical validity is still controversial. The aim of this article is to describe and analyze the clinical validity of histological analysis in the diagnosis of prosthetic infection in patients undergoing hip or knee prosthetic replacement.
MATERIAL AND METHODS: We present a retrospective study including 133 hip and knee prosthetic replacements performed in our center between 2008 and 2020. A descriptive, bivariate statistical analysis was performed and the clinical validity of the histological analysis was determined.
OUTCOMES: The clinical validity of the intraoperative histology offered a sensitivity of 48%, a specificity of 91%, a positive predictive value of 55% and a negative predictive value of 88%.
CONCLUSIONS: The determination of the clinical validity of histological analysis shows a high specificity. This analysis is an appropriate diagnostic tool for detecting healthy patients, with no infection.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:67 |
|---|---|
| Enthalten in: |
Revista espanola de cirugia ortopedica y traumatologia - 67(2023), 1 vom: 01. Jan., Seite 21-26 |
| Sprache: |
Englisch |
|---|
| Weiterer Titel: |
Validez clínica de la histología intraoperatoria en el diagnóstico de la infección protésica |
|---|
| Beteiligte Personen: |
Fernández-Hijano, M R [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Artroplastia cadera |
|---|
| Anmerkungen: |
Date Completed 06.01.2023 Date Revised 11.01.2023 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.recot.2022.07.012 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM34383717X |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM34383717X | ||
| 003 | DE-627 | ||
| 005 | 20231226021359.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.recot.2022.07.012 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1146.xml |
| 035 | |a (DE-627)NLM34383717X | ||
| 035 | |a (NLM)35863722 | ||
| 035 | |a (PII)S1888-4415(22)00196-5 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Fernández-Hijano, M R |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Clinical validity of the intraoperative histology in the diagnosis of prosthetic joint infection |
| 246 | 3 | 3 | |a Validez clínica de la histología intraoperatoria en el diagnóstico de la infección protésica |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 06.01.2023 | ||
| 500 | |a Date Revised 11.01.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2022 SECOT. Publicado por Elsevier España, S.L.U. All rights reserved. | ||
| 520 | |a BACKGROUND AND AIM: Different authors have demonstrated the usefulness of the histological analysis in the diagnosis of prosthetic joint infection; however, its clinical validity is still controversial. The aim of this article is to describe and analyze the clinical validity of histological analysis in the diagnosis of prosthetic infection in patients undergoing hip or knee prosthetic replacement | ||
| 520 | |a MATERIAL AND METHODS: We present a retrospective study including 133 hip and knee prosthetic replacements performed in our center between 2008 and 2020. A descriptive, bivariate statistical analysis was performed and the clinical validity of the histological analysis was determined | ||
| 520 | |a OUTCOMES: The clinical validity of the intraoperative histology offered a sensitivity of 48%, a specificity of 91%, a positive predictive value of 55% and a negative predictive value of 88% | ||
| 520 | |a CONCLUSIONS: The determination of the clinical validity of histological analysis shows a high specificity. This analysis is an appropriate diagnostic tool for detecting healthy patients, with no infection | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Artroplastia cadera | |
| 650 | 4 | |a Artroplastia rodilla | |
| 650 | 4 | |a Hip replacement | |
| 650 | 4 | |a Histopathology | |
| 650 | 4 | |a Histopatología | |
| 650 | 4 | |a Infección protésica | |
| 650 | 4 | |a Knee replacement | |
| 650 | 4 | |a Prosthetic infection | |
| 700 | 1 | |a Gómez-Palomo, J M |e verfasserin |4 aut | |
| 700 | 1 | |a Arranz-Salas, I |e verfasserin |4 aut | |
| 700 | 1 | |a Hierro-Martín, M I |e verfasserin |4 aut | |
| 700 | 1 | |a Zamora-Navas, P |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Revista espanola de cirugia ortopedica y traumatologia |d 2012 |g 67(2023), 1 vom: 01. Jan., Seite 21-26 |w (DE-627)NLM222862793 |x 1988-8856 |7 nnns |
| 773 | 1 | 8 | |g volume:67 |g year:2023 |g number:1 |g day:01 |g month:01 |g pages:21-26 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.recot.2022.07.012 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 67 |j 2023 |e 1 |b 01 |c 01 |h 21-26 | ||