Is the Rheumatoid Arthritis Impact of Disease (RAID) score a meaningful instrument for other inflammatory rheumatic diseases? A cross-sectional analysis of data from the German National Database
© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ..
ObjectiveTo analyse the performance of the rheumatoid arthritis impact of disease (RAID) score in patients with ankylosing spondylitis, polymyalgia rheumatica, systemic lupus erythematosus, primary Sjögren's syndrome, idiopathic inflammatory myositis and systemic sclerosis, as compared with rheumatoid arthritis (RA).MethodsA total of 12 398 patients from the German National Database were included. For each diagnosis, we calculated age-adjusted/sex-adjusted partial correlation coefficients between RAID and patient global (PtGl) health, PtGl disease activity, physician global (PhGl) disease activity, Well-Being Index (WHO-5) and EuroQoL-5 Dimensions (EQ-5D). As a measure of agreement, the mean differences between the RAID and other outcomes were compared with the respective differences for RA. The effect of each diagnosis on the difference between RAID and the other scores was assessed with linear regression, with RA as the reference.ResultsAcross all diagnoses, RAID correlated strongly with PtGl health (0.71-0.83), moderately to strongly with PtGl disease activity (0.59-0.79), WHO-5 (0.65-0.81) and EQ-5D (0.68-0.73) and weakly with PhGl disease activity (0.23-0.38). Mean differences were calculated for RAID and PtGl disease activity (0 to -0.6), PtGl health (-0.4 to -0.9), WHO-5 (-0.7 to -1.3), EQ-5D (1.1 to 1.7) and PhGl disease activity (1.4 to 2.2). Discrepancies between other scores and RAID were comparable to RA. Linear regression revealed no clinically relevant effect of any of the diagnoses on the difference between RAID and the other outcomes.ConclusionThe RAID score performs comparably across all diagnoses investigated. This supports the use of RAID for measuring the impact also of other rheumatic diseases.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2022 |
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Erschienen: |
2022 |
Enthalten in: |
Zur Gesamtaufnahme - volume:8 |
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Enthalten in: |
RMD open - 8(2022), 2 vom: 12. Juli |
Sprache: |
Englisch |
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Beteiligte Personen: |
Thiele, Katja [VerfasserIn] |
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Links: |
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Themen: |
Arthritis, rheumatoid |
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Anmerkungen: |
Date Completed 08.07.2022 Date Revised 26.07.2022 published: Print Citation Status MEDLINE |
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doi: |
10.1136/rmdopen-2022-002342 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM343145006 |
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245 | 1 | 0 | |a Is the Rheumatoid Arthritis Impact of Disease (RAID) score a meaningful instrument for other inflammatory rheumatic diseases? A cross-sectional analysis of data from the German National Database |
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520 | |a ObjectiveTo analyse the performance of the rheumatoid arthritis impact of disease (RAID) score in patients with ankylosing spondylitis, polymyalgia rheumatica, systemic lupus erythematosus, primary Sjögren's syndrome, idiopathic inflammatory myositis and systemic sclerosis, as compared with rheumatoid arthritis (RA).MethodsA total of 12 398 patients from the German National Database were included. For each diagnosis, we calculated age-adjusted/sex-adjusted partial correlation coefficients between RAID and patient global (PtGl) health, PtGl disease activity, physician global (PhGl) disease activity, Well-Being Index (WHO-5) and EuroQoL-5 Dimensions (EQ-5D). As a measure of agreement, the mean differences between the RAID and other outcomes were compared with the respective differences for RA. The effect of each diagnosis on the difference between RAID and the other scores was assessed with linear regression, with RA as the reference.ResultsAcross all diagnoses, RAID correlated strongly with PtGl health (0.71-0.83), moderately to strongly with PtGl disease activity (0.59-0.79), WHO-5 (0.65-0.81) and EQ-5D (0.68-0.73) and weakly with PhGl disease activity (0.23-0.38). Mean differences were calculated for RAID and PtGl disease activity (0 to -0.6), PtGl health (-0.4 to -0.9), WHO-5 (-0.7 to -1.3), EQ-5D (1.1 to 1.7) and PhGl disease activity (1.4 to 2.2). Discrepancies between other scores and RAID were comparable to RA. Linear regression revealed no clinically relevant effect of any of the diagnoses on the difference between RAID and the other outcomes.ConclusionThe RAID score performs comparably across all diagnoses investigated. This supports the use of RAID for measuring the impact also of other rheumatic diseases | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Research Support, Non-U.S. Gov't | |
650 | 4 | |a arthritis, rheumatoid | |
650 | 4 | |a outcome assessment, health care | |
650 | 4 | |a patient reported outcome measures | |
700 | 1 | |a Albrecht, Katinka |e verfasserin |4 aut | |
700 | 1 | |a Zink, Angela |e verfasserin |4 aut | |
700 | 1 | |a Aringer, Martin |e verfasserin |4 aut | |
700 | 1 | |a Karberg, Kirsten |e verfasserin |4 aut | |
700 | 1 | |a Späthling-Mestekemper, Susanna |e verfasserin |4 aut | |
700 | 1 | |a von Hinüber, Ulrich |e verfasserin |4 aut | |
700 | 1 | |a Callhoff, Johanna |e verfasserin |4 aut | |
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