White blood segmentation based on dual path and atrous spatial pyramid pooling

The count and recognition of white blood cells in blood smear images play an important role in the diagnosis of blood diseases including leukemia. Traditional manual test results are easily disturbed by many factors. It is necessary to develop an automatic leukocyte analysis system to provide doctors with auxiliary diagnosis, and blood leukocyte segmentation is the basis of automatic analysis. In this paper, we improved the U-Net model and proposed a segmentation algorithm of leukocyte image based on dual path and atrous spatial pyramid pooling. Firstly, the dual path network was introduced into the feature encoder to extract multi-scale leukocyte features, and the atrous spatial pyramid pooling was used to enhance the feature extraction ability of the network. Then the feature decoder composed of convolution and deconvolution was used to restore the segmented target to the original image size to realize the pixel level segmentation of blood leukocytes. Finally, qualitative and quantitative experiments were carried out on three leukocyte data sets to verify the effectiveness of the algorithm. The results showed that compared with other representative algorithms, the proposed blood leukocyte segmentation algorithm had better segmentation results, and the mIoU value could reach more than 0.97. It is hoped that the method could be conducive to the automatic auxiliary diagnosis of blood diseases in the future.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:39

Enthalten in:

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi - 39(2022), 3 vom: 25. Juni, Seite 471-479

Sprache:

Chinesisch

Beteiligte Personen:

Li, Zuoyong [VerfasserIn]
Lu, Yan [VerfasserIn]
Cao, Xinrong [VerfasserIn]
Qiu, Lida [VerfasserIn]
Qin, Xuejun [VerfasserIn]

Links:

Volltext

Themen:

Atrous spatial pyramid pooling
Convolutional neural network
Dual path network
Image segmentation
Journal Article
White blood cell segmentation

Anmerkungen:

Date Completed 06.07.2022

Date Revised 22.03.2024

published: Print

Citation Status MEDLINE

doi:

10.7507/1001-5515.202107043

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM343091909